supplements

Rutin - Rutoside

What is Rutina

Rutin or rutoside is a natural substance, a flavonoic glycoside found in plants belonging to different families, especially that of the Rutaceae (it is not by chance that it takes its name from the Ruta - Ruta graveolens ).

The most exploited sources for their rutin content are the buds of Sophora japonica (15-20%), the leaves of Eucalyptus macrorhyncha (about 10%) and those of Fagopyrum esculentum (buckwheat, 5-8%). Common foods rich in rutin include asparagus, citrus fruits (especially their rind) and wild berries such as blackberries and blueberries.

Property

Rutin and rutoside are sometimes improperly called vitamin P, emphasizing its great effectiveness in regulating the permeability of blood capillaries. It is no coincidence that they are also used in registered medicinal products to maintain the physiological permeability and tropism of the capillaries; in particular conditions, such as hemorrhoids, the ability of rutin to act as an anti-haemorrhagic and anti-edema may therefore have an important therapeutic role. In this sense rutin shares the same properties as quercetin, a flavonoid contained in its molecule (as an aglycone) together with a sugary part (rutinosio).

Loans

In addition to the anti-haemorrhoidal treatment, rutin is also used to provide relief from symptoms related to poor circulation in the lower limbs (edema, itching, redness, varicose veins).

As an antioxidant, rutin is able to bind to bivalent iron (Fe2 +) preventing its binding with hydrogen peroxide (H 2 0 2 ); this reaction would generate highly reactive free radicals. Due to its antioxidant, antiplatelet and anti-thrombotic properties (making the blood "more fluid"), rutin is included in a wide variety of supplements designed to promote cardiovascular health, for example in the presence of high cholesterol, obesity or reduced tolerance to glucose.

Its ability to act as an inhibitor of angiogenesis (development of new blood vessels from existing ones), makes rutin a current object of study for possible anticancer properties.