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phytotherapy

Pineapple: Contraindications and Bibliography

By Dr. Rita Fabbri

Contraindications, special warnings and appropriate precautions for use, undesirable effects

For the Pineapple, we have no clinical studies conducted on pregnant and lactating women; in these cases it is therefore advisable to inform the doctor before taking products containing it. Pineapple preparations are contraindicated in subjects with peptic ulcer and in patients on anticoagulant therapy (59). Bromelain may increase the absorption of tetracycline and amoxicillin:

  • In a double-blind study of 127 patients, bromelain significantly increased serum levels of amoxicillin compared to the control group treated with amoxicillin and placebo. Furthermore, significantly higher amoxicillin tissue levels were found in the Bromelain group (47).

Similar results for both amoxicillin and tetracyclines were reported in a placebo-controlled study in 54 patients treated with bromelain (46).

Although no significant side effects are known, allergic reactions may occur in sensitive individuals or those exposed for professional reasons (60-61). Other possible reactions, even if not confirmed, include nausea, vomiting, diarrhea, metrorrhagia and menorrhagia (62).

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