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Gymnema: summary of the properties of Gymnema

Scroll down the page to read the summary table on gymnema.

Gymnema: etymology of the term Gymnema: derives from "Gur mar", a term that, literally translated into Hindu, refers to "eat sugar" → in ancient folk medicine, it was recommended to chew gymnema leaves to reduce glycosuria
Gymnema: main properties and popular uses Useful in the treatment of diabetes

Also used in the treatment of hemorrhoids, cardiac deficits and eye defects

Gymnema: botanical description
  • Botanical name: Gymnema sylvestris
  • Family: Asclepiadaceae
  • Description: typical climbing plant
  • Origin: Central Africa
  • Diffusion: widespread in all continents except the American one
  • Branches: dense
  • Leaves: opposite, petiolate, oval, sometimes elliptical
  • Flowers: typically bell-shaped and united in pedunculate racemes
Gymnema: drug Leaves: characteristic bitter and acrid taste
Gymnema: description of the phytocomplex
  • Gymnemic acids (gymnemic acid and deacylgymnemic) → antidiabetic properties
  • Four saponins of gymnemic acid
  • Phytosterols
  • pectin
  • Conduritol A
  • Gurmarine → anti-softening polypeptide
Gymnema: property
  • Antidiabetic (hypoglycemic)
  • Pancreatic (stimulates pancreatic function)
  • cholesterol lowering
  • Alteration of the perception of sweet taste
  • antibacterial
  • Antiemorroidaria
  • Diuretic
  • Laxative and stimulants
  • Eye improvement activities
  • Anti-obesity and slimming
Gymnema and hypoglycemic activity Gymnema exercises its hypoglycemic action:
  • In the treatment of insulin-independent diabetes mellitus
  • Exercising the same mechanism of action of synthetic drugs with oral hypoglycemic action
Gymnema and gymnemic acid It exerts its action in diabetes mellitus:
  • Reducing plasma glucose levels by stimulating pancreatic insulin secretion
  • Favoring the regeneration of pancreatic beta cells
  • Reversible blocking of the enteric glucose receptor
  • Reducing the absorption of sugars
  • Inhibiting the action of pancreatic and intestinal amylases
Gymnema and gurmarina Gurmarine: polypeptide responsible for the anti-sweetening activity:
  • acts by topical application on the tongue
  • alters the normal functionality of the taste buds
  • inhibits the taste for sweet, NOT the one for salty or acid
Gymnema and toxicity No toxic effects are recorded following the administration of gymnema in pregnant or lactating women → it is a good rule, however, to consult the doctor

Strengthening of the hypoglycemic effect of antidiabetic drugs taken at the same time → modulation of the dosage