doping

Anabolic Steroids: Side Effects

Before reading the article on - Anabolic Steroids: Side effects - make sure you are aware of the side effects and the legal repercussions arising from the use of anabolic steroids (regulated by the anti-doping law December 14, 2000, No. 376 and subsequent updates, and by the law concerning the discipline of narcotics DPR 9 October 1990, No. 309 and subsequent updates)

By Dr. Nicola Sacchi - Author of the book: Drugs and doping in sport -

For those who think that some anabolic does not have any side effects

Many users of anabolic steroids live in the absolute belief that "some injections" do not hurt, that it is enough not to overdo it in order to have no side effects, that there are more dangerous products and others that almost do not present any risk, etc. etc. The idea of ​​the concept of "moderate use" is often supported by some so-called doping experts who publish "instructions for use", extolling the ability to control the side effects of anabolics.

This misconception that moderate use - if moderate can be talked about when using supra-physiological and supra-therapeutic doses of substances born to treat certain pathologies, without any medical motivation (since chemicals created to treat certain ailments, are used only for increase your muscle mass - both safe and secure, often leading to the use of anabolic steroids by people unaware of what they are actually doing with their body.

Beyond popular beliefs, an interesting scientific study demonstrates how ONE INJECTION OF 100 MG OF NANDROLONE REDUCES THE ENDOGENOUS PRODUCTION OF TESTOSTERONE MEASURED TO BRING THE EMATICAL LEVELS OF THE SAME TO A FOURTH OF NORMAL THOSE. In other words, it reduces natural testosterone production by 75%, bringing blood levels from 20 nM to 5 nM.

The study in question, not even so new since it is from 1997, is:

Minto CF, Howe C, Wishart S, Conway AJ, Handelsman DJ.

Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle: effects of ester, injection site and injection volume.

J Pharmacol Exp Ther. 1997 Apr; 281 (1): 93-102.

Dr. Minto and colleagues examine a sample of subjects who are given a dose of 100 mg of nandrolone with two different forms of esterification (phenylpropionate and decanoate). The esterification determines the release times of the substance, which in order to become active must be separated from the molecule to which it is esterified. Basically, the different esterification determines the different duration of action of the drug. Furthermore, the study examines how the action of nandrolone can change depending on the muscle in which it is injected.

The value examined in the study is the blood concentration of testosterone, which, following the injection, drops dramatically and then rises again after more than 20 days.

The reported study also analyzes other data not important for the purposes of this article, which therefore will not be mentioned.

The graph below shows the trend in blood testosterone concentration in the days following the injection.

the graph shows how ONE INJECTION of 100 mg of nandrolone alters blood testosterone levels for about 20/25 days; it is also shown how this value changes according to the type of ester (phenylpropioinate or decanoate) and the injection site (Minto).

Substantially the different esterifications cause a recovery of blood levels of different testosterone, in fact the phenylpropionate, which releases nandrolone more rapidly, determines a more rapid recovery. While the different injection sites determine a very similar testosterone fluctuation.

The fundamental fact on which to reflect remains the fact that the testosterone produced by the body is dramatically reduced within 3/4 days and remains at a quarter of the level before the injection for another 10/20 days. Another fact perhaps even more interesting is that to bring testosterone levels back to normal it is necessary to pass about 20/25 days from the time of injection. And all this after just a 100 mg injection of nandrolone, not a 4 or 6 or 8 or 10 or 12 week cycle of a stack of different anabolics, but after just one injection!

This is what really happens when steroids are used.

These indications are for informational purposes only and are NOT intended in any way to replace the opinion of a doctor or to favor the use of anabolic steroids, nor to promote specific commercial products, possibly indicated for informational purposes only. The use of anabolic steroids outside the medical field is a dangerous and aberrant practice from which we depart CONDANNANDOLA E SCORAGGIANDOLA in the most absolute way. In this regard, see the list of generic side effects related to anabolic steroids or what is published at the bottom of the article.

Any posology and methods of use indicated with regard to use in sports or beauty, do NOT have the value of specific advice; they intend to provide information of a general nature in line with what is disseminated by scientific publications on the subject (see bibliography or other texts on doping), to limit phenomena of abuse, it being understood that there is no safe and free dosage or combination of drugs of side effects. For these reasons the author declines all responsibility for damages, claims or losses, direct or indirect, deriving from the use of such information.

Some of the most common side effects you may experience using Anabolic Steroids ...

Clinical case: severe acne conglobata induced by androgenic anabolic steroids.

A) The patient at the time of his ideal body image; the 21-year-old bodybuilder has had a history of androgenic anabolic steroid abuse. B) Severe conglobate acne; lesions include papules, pustules, abscesses and deep ulcerations. C) Patient after six weeks of antiseptic antibiotic therapy (note the permanent scarring). Source: Lancet

Gynecomastia, a medical term indicating the abnormal growth of breast tissue in humans (side image), is another macroscopic side effect of anabolic steroids. If not addressed promptly with a suitable pharmacological therapy, this condition is almost irreversible; the only valid solution is a specific surgical procedure.

In genetically predisposed subjects, androgenetic alopecia ("hair loss") and excessive growth of body hair represent further undesirable macroscopic effects of these substances.

Other side effects of anabolic steroids include: hypertension, temporary infertility in men, atrophy (shrinking) of the testicles, hypertrichosis and virilism (in women, hair growth and male sexual characteristics), menstrual changes, severe developmental anomalies fetal (if taken during pregnancy), growth block (if taken during adolescence), liver dysfunctions, increased cardiovascular risk, increased aggression and outbursts of anger up to real psychosis and physical dependence in case of prolonged use (homicidal thoughts and attitudes during the assumption, suicidal thoughts and attitudes during abstinence). The psycho-physical dependence on these substances means that, even when starting a low-dose intake cycle to limit possible side effects, the user - however informed and "conscientious" - could fall into a vicious circle whereby, with increasing doses and time taken for intake, the side effects would become more and more serious and obvious, leading to extreme cases, for this reason only apparently "exaggerated", highlighted in the photos.