Acetyl carnitine plus - Ultimate Italia

Information on Acetyl carnitine plus - Ultimate Italia

Food supplement of acetyl L carnitine.

FORMAT

90 cps bottle

COMPOSITION

Acetyl L-Carnitine HCL: stable form of the active ingredient

Calcium pantothenate (Vitamin B5)

Vitamin B6

Vitamin B2

Capsule: edible gelatin

Excipient: Magnesium stearate.

One capsule contains:

Acetyl L-Carnitine 200 mg - ALC ( Acetyl L-Carnitine ) represents the trimethylated ester of the most common L-Carnitine; it is produced at the mitochondrial level by renal, hepatic and cerebral cells, starting from L-Carnitine and an acetyl group. The presence of an acetyl residue makes the active ingredient more easily absorbable, so that studies show that supplementation of 2gr / day can produce an increase in blood levels of 43%. The ALC is able to guarantee, through the mitochondrial membrane, the regeneration of L-carnitine and the transfer of an acetyl group for oxidative purposes, with consequent strengthening of lipid metabolism. L-carnitine and its acyl ester function as fatty acid transporters in the mitochondrial matrix, promoting the B-oxidation process. Furthermore, the mimetic colander action also allows an important activation of neuronal mitochondrial metabolism, preserving it from degeneration.

Calcium pantothenate 5 mg - also known as Vitamin B5, is part of the synthesis of Coenzyme A (ATP + VitB5 + Cys), which plays a key role in all reactions involving the transfer of an acyl group (pyruvate oxidative decarboxylation, of α-ketoglutarate, oxidation of fatty acids). It therefore has a central role in both carbohydrate and lipid metabolism. The recommended daily dose ranges from 4 mg to 7 mg; however, given the presence of this vitamin in many foods (mainly whole grains), deficiencies are found only in serious cases of malnutrition.

Pyridoxine (Vitamin B6) 1 mg - pyridine derivative introduced mainly through meat; it is absorbed at the level of the fast, after dependent ATP hydrolysis and reaches the liver bound to albumin. Here it is transformed into pyridosamine and then into pyridoxal and subsequently phosphorylated, with consequent activation and storage. From the liver it will then be released in a non-phosphorylated circle, to reach various tissues where, once rephosphorylated, it will be able to fulfill its biological role. In fact, vitamin B6 participates as a coenzyme in numerous reactions mainly involved in amino acid metabolism (transamination and oxidative deamination), lipid (sphingolipid synthesis) and glucidic.

Its daily requirement is around 1 / 1.5 mg, but even in this case the cases of deficiency are very rare.

Riboflavin (Vitamin B2) 0.85 mg - introduced mainly through eggs, milk and derivatives, vegetables is absorbed in the intestine, after having been dephosphorylated. By binding to albumin, but also to Ig, it reaches the liver, where it is transformed into the coenzymatic forms FMN and FAD.

These two prosthetic groups, essential for metabolism in general, are part of the process of oxidative decarboxylation of pyruvate, in the krebs cycle, in the B-oxidation of fatty acids, in the oxidation of amino acids and in oxidative phosphorylation.

The recommended daily dose is 0.6 mg every 1000 kcal introduced with the diet.

Product features Acetyl carnitine plus - Ultimate Italia

This supplement, in addition to providing acetyl L carnitine in the dosage of 200mg per capsule, also guarantees the contribution of three essential vitamins in the oxidative processes. The intent would be to provide some of the elements necessary to support the oxidative metabolism, and in particular the lipid metabolism, thus optimizing the use of fatty acids for energy purposes.

Recommended use by the company - Acetyl carnitine plus - Ultimate Italia

1 cps per day in a little water.

Use in sports Acetyl carnitine plus - Ultimate Italia

In sports practice the dosages usually recommended range from 500 mg to 2 / 2.5 g, taken in divided doses during the day, and increasing or decreasing weekly. Studies on the pharmacokinetics of carnitine show that the alimentary one exhibits a bioavailability of over 75% (54-87%), probably due to the modest doses present in food and above all to transport (cotrasporto with sodium) intestinal ALC mediated by the transporter OCTN2 ; on the other hand, the bioavailability of the carnitine present in the supplements amounts to minimum values ​​(14-18% for L-carnitine). This could suggest, the possibility of taking this supplement with meals, even if the limiting factor is not so much the intestinal absorption, as its storage at the muscular level, not yet completely characterized.

Rationale for use - Acetyl carnitine plus - Ultimate Italia

Recent studies show the ability of ALC to preserve and sustain aerobic muscle capacity (study carried out on rats); this could be a start for a more detailed evaluation of its effects in sports practice or in facilitating the slimming process. Although acetyl L carnitine has been shown to be effective in improving aerobic muscle performance in rats subjected to exercise, in reducing fatigue in patients with multiple sclerosis and in reducing oxidative glucose markers after intense physical effort, there are no studies in the literature to prove the ergogenic properties of this supplement on healthy individuals, as well as studies lacking in association with vitamin elements.

Side effects Acetyl carnitine plus - Ultimate Italia

At high doses episodes of insomnia, nausea, abdominal cramps, migraine and gastro intestinal disorders may occur, albeit rare.

Precautions for use Acetyl carnitine plus - Ultimate Italia

Contraindicated in cases of renal, hepatic, diabetic, pregnancy, lactation, mood disorders.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of Acetyl carnitine plus - Ultimate Italia.