NAC, Now Foods - N Acetyl Cysteine

Information on NAC, Now Foods - N Acetyl Cysteine

Food supplement based on N Acetyl Cysteine

FORMAT

100 cps bottle

COMPOSITION

NAC

Molybdenum (amino acid chelate)

Selenium (selenomethionine)

Capsule: gelatin

Stearic acid and citric acid

One capsule contains: NAC 600 mg

Molybdenum 50 mcg

Selenium 25 mcg

N-Acetyl Cysteine ​​200mg - together with glutamate and glycine, it is part of the most powerful antioxidant synthesis available to us: glutathione. The low bioavailability of food cysteine ​​makes this amino acid the limiting factor in the synthesis of glutathione, as well as the oral integration of this early degraded and inactivated tripeptide. N acetyl cysteine, on the other hand, can be effectively absorbed in the intestine and made available at the cellular level, where it regenerates cysteine ​​following deacetylation.

Already in itself, NAC takes on antioxidant properties, but the demonstrated ability to increase endogenous glutathione levels makes this supplement one of the most efficient oxidative damage fighters. In fact, numerous therapeutic applications have been tested, aimed at reducing the oxidative insult generated in pathologies such as neurodegenerative and tumoral diseases, as well as the anti-flu and mucolytic properties, which make it one of the best-selling drugs (see fluimucil ®)

Like other antioxidants, it has also proven effective in counteracting the action of ROS following intense physical activity, preserving cellular structures and enhancing the organic pull of endogenous antioxidants.

Molybdenum 50mcg - Trace element present in both animals and plants. Within the human organism it is a cofactor in various enzymatic reactions involved in the metabolism of sulfur amino acids (methionine and cysteine), in the degradation of nucleotides to uric acid and in hepatic detoxification processes from drugs and toxins. Present mainly in meat, legumes and whole grains, it is absorbed in the intestine, and made available as a cofactor.

The recommended intake levels range from 50 to 150 mcg per day, but cases of molybdenum deficiency (concentrated in individuals with gastro-intestinal tract diseases) are very rare.

Dosages higher instead of 10/15 mg per day, have proved dangerous for the onset of gout, while a case of psychosis, hallucinations, and behavioral disorders following the daily intake of 300 / 800mcg is documented.

Supplementation with molybdenum, however, has proven to be useful in preventing esophageal and gastric cancer and tooth decay, at dosages in any case comparable to the normal daily requirement.

Furthermore, several studies highlight the potential antioxidant properties of this trace element.

Selenium 25mcg: it is very present in nature, in Brazilian nuts, in fish, in meats and in some vegetables such as broccoli. It is easily absorbed in the intestine and incorporated by the cells, where it is a coenzyme of selenium proteins. The form present in this supplement, seleniomethionine, is among the most bioavailable, recording absorption levels of 90% of the ingested dose.

As a cofactor it is part of numerous compounds, for example regulating the metabolism of thyroid hormones (in fact it acts together with desiodase, generating the active form of the thyroid hormone (T3)), but above all it is part of the mechanisms of protection of oxidative damage (glutathione peroxidase and thyroidine reductase).

The various isoforms of glutathione peroxidase, in fact, require selenium to carry out their antioxidant function, thus being able to neutralize the damage caused by reactive oxygen species. Supplementation with selenium has proved useful in enhancing the immune defenses even in healthy individuals, and in counteracting the tumor onset, through different mechanisms, not yet completely clear, but at the base of which there is certainly the powerful antioxidant role. Furthermore, a potential role in the prevention of liver disease and cardiovascular disease is also being ascertained.

The requirement of this element is ascertained between 50/70 mcg per day, a value that can be reached through a healthy diet. Deficiencies are very rare, however associated with severe malnutrition, parenteral feeding and diseases of the intestinal gastrointestinal tract.

The currently defined maximum safe dose, due to the absence of side effects, is about 400 mcg / day. At higher dosages gastro intestinal disorders, fatigue, skin rash, problems affecting the nervous system occur.

In sporting practice, the integration between 100 and 400mcg per day of selenium has proved to be effective. in several studies, in reducing markers of oxidative damage following exercise.

Product features NAC, Now Foods - N Acetyl Cysteine

The product in question combines two major trace elements with N acetyl cysteine, which represents the main active ingredient. Very interesting, in fact, is the presence of selenium, which together with glutathione produces glutathione peroxidase, a scavanger of ROS, thus providing another useful element to assist the functionality of this powerful antioxidant.

In the same perspective of prevention of oxidative damage, molybdenum is also added, although unlike the first two substances there are still no studies showing the effectiveness of this element in reducing oxidative damage following intense physical activity.

Recommended use by the company - NAC, Now Foods - N Acetyl Cysteine

1 cps per day during meals

Use in sports NAC, Now Foods - N Acetyl Cysteine

Various studies have tested the effectiveness of supplementation with NAC in sports practice.

The dosages found in these studies start at 600 mg / day and reach 1.2 / 1.8 g / day on training days. In the same, the timing of administration varies from 2 weeks to 6 weeks.

Selenium, on the other hand, is generally used at doses of 100 mcg a day, able - together with other antioxidants - to counteract oxidative damage.

Rationale for use - NAC, Now Foods - N Acetyl Cysteine

This type of supplement finds only one use, justified and supported by scientific studies in sports, that of ANTIOXIDANT.

Physical activity, especially when exercised in aerobic conditions, represents an important source of reactive oxygen species, which in excess can exert a deleterious effect during physical performance (fatigue) and on the other oxidize cellular structures, reducing recovery capacities. Under normal conditions our body is able to counteract this effect, but studies have shown that supplementation with antioxidant agents can support the body at this stage, reducing oxidative markers and enhancing endogenous protective capacities.

Side effects NAC, Now Foods - N Acetyl Cysteine

No particular side effects of oral supplementation with NAC have been recorded even for prolonged periods.

However, strict medical supervision is required in the case of asthmatic individuals, with respiratory tract affections or with diseases of the gastrointestinal tract.

Intake of the product may occasionally be followed by nausea, vomiting or hypersensitivity reactions such as hives and bronchospasm.

Important side effects are recorded for molybdenum at high doses (10 / 15mg), while for selenium dosages around 400mcg / day have been defined as safe.

Interactions

may interfere with various types of antibiotics if taken at the same time.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of NAC, Now Foods - N Acetyl Cysteine.