LENTO-KALIUM ® - Potassium

LENTO-KALIUM ® is a potassium chloride drug

THERAPEUTIC GROUP: Minerals - Potassium

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications LENTO-KALIUM ® - Potassium

LENTO-KALIUM ® is used in the prevention and treatment of potassium deficiencies associated with prolonged use of diuretics, the abuse of laxatives and the presence of prolonged diarrhea or vomiting.

LENTO-KALIUM ® can also be used in cases of digitalis intoxication or in the treatment of hypopotassemia and hypocloremic metabolic alkalosis.

Mechanism of action LENTO-KALIUM ® - Potassium

Potassium is a precious electrolyte for controlling the activity of cells, tissues, organs and systems.

Its importance in the cellular economy is due to the role of:

Enzymatic cofactor, necessary for the correct functioning of numerous enzymes involved mainly in carbohydrate metabolism;
Main intracellular ion, necessary to maintain the correct membrane potential, and consequently the related phenomena of excitation and conduction of nerve impulses.

LENTO-KALIUM ® supplies this element in the form of potassium chloride, salt not only able to supply potassium but also to replenish chlorine, thus contributing to the maintenance of a better electrolyte balance, useful for safeguarding the health of the cell.

Moreover this medicine, thanks to the presence of a particular chemical formulation, allows to release the aforesaid salt, slowly and homogeneously, thus avoiding the formation of deposits and the related irritative effects on the gastric mucosa.

Studies carried out and clinical efficacy

1.PASSASSIUS AND DIABETES

Diabetologia. 2012 Feb 10.

Low potassium intake is associated with an increased risk of developing type II diabetes, especially in African-American patients. In these cases therefore, potassium supplementation could have an important preventive role.

2. THE POTASSIUM AND THE KIDNEY FUNCTIONALITY

Scand J Clin Lab Invest. 2012 Feb; 72 (1): 78-86.

Work demonstrating how supplementation with potassium can influence renal function, improving water absorption and increasing tubular function in the distal part of the nephron, without this leading to an increase in blood pressure

3. POTASSIUM IN KALA-AZAR THERAPY

Am J Trop Med Hyg. 2010 Nov; 83 (5): 1040-3.

The adjuvant action of potassium in the pharmacological therapy of Kala-azar (visceral leishmaniasis) has been shown to be effective in reducing the side effects at the renal level, monitored with blood creatinine concentrations induced by amphotericin B.

Method of use and dosage

LENTO-KALIUM ®

Hard capsules for oral use containing 600 mg of potassium chloride.

Generally we recommend taking 1 - 2 capsules for two - three times a day.

In reality the dosage used should be established by the doctor after assessing the patient's needs, the clinical picture and the amount of this element taken through the diet.

It is advisable to take LENTO-KALIUM ® on a full stomach in order to reduce irritation of the gastric mucosa.

Warnings LENTO-KALIUM ® - Potassium

The use of LENTO-KALIUM ® should be preceded by a careful medical examination to assess the patient's overall health, the possible presence of hyperkalemia and reduced renal function.

In the aforementioned cases the administration of this medicine could be contraindicated or if necessary, strictly subordinate to the constant supervision of your doctor.

Some of the side effects expected for potassium salts could aggravate pre-existing complications at the level of the gastric mucosa.

Treatment should always be associated with monitoring of plasma electrolytes.

PREGNANCY AND BREASTFEEDING

The use of LENTO-KALIUM ® during pregnancy and in the subsequent period of breastfeeding should be carried out exclusively in case of real need and under strict medical supervision.

Interactions

LENTO-KALIUM ® can be used during pregnancy and in the subsequent period of lactation, exclusively under strict medical supervision.

Contraindications LENTO-KALIUM ® - Potassium

The use of LENTO-KALIUM ® is contraindicated in case of hypersensitivity to the active ingredients or to the relative excipients, hyperkalemia, renal and adrenal insufficiency, uremia, dehydration, diabetic acidosis, reduced gastrointestinal motility and hereditary periodic adinamia.

Undesirable effects - Side effects

Despite the particular pharmaceutical formulation envisaged for LENTO-KALIUM ® it allows to significantly reduce the side effects associated with the use of potassium chloride, it is useful to remember how this salt could cause the appearance of nausea, diarrhea, gastrointestinal pain and in more serious cases damage to the gastric mucosa with gastrointestinal obstruction or perforation.

Overdose may instead be responsible for hyperkalaemia with both renal and cardiac complications.