Nitric Ram - Prolabs

Information about Nitric Ram - Prolabs

Nitric Ram - Prolabs

Food supplement of branched chain amino acids with Vitamin B6 and arginine.

FORMAT

Pack of 140 tablets

INGREDIENTS: L-Arginine - L-Leucine - L-Isoleucine - L-Valine - Emulsifier: Microcrystalline Cellulose - Anti-caking agents: silica, Magnesium stearate - Vitamin B6.

For 7 tablets: L-Arginine 3000 mg - L-leucine 2500 mg - L-valine 1250 mg - L-isoleucine 1250 mg - Vitamin B6 0.6 mg

Branched chain amino acids - group consisting of three essential amino acids: leucine, isoleucine and valine. As essential, it is necessary to provide for their introduction through a diet, which can be quite simple given the abundant presence both in products of animal and vegetable origin. A balanced diet, which brings about 360 Kcal in protein, is able to provide as much as 9 grams of branched chain amino acids, and thus satisfy most of the organic demands of these molecules.

Their importance from the biochemical - physiological point of view must be traced back to:

1. Anabolic role: fall within the processes of protein synthesis;
2. Energy role: they are the preferred oxidative substrate of the body and in particular of the muscular tissue, after carbohydrates and lipids;
3. Gluconeogenic role: they are able to support the synthesis of glucose, through common precursors such as pyruvate and oxalacetate, or by increasing alanine levels and accelerating the myo-hepatic glucose-alanine cycle;
4. Plastic and structural role: fall within the restoration of muscle myofibrils;
5. "Detoxifying" role: increase levels of circulating glutamine.

Along with these general characteristics, the numerous scientific evidences that support the hypothesis of a hormonal and anti-fatigue regulatory role must also be considered.

BCAA and Sport

Several publications have shown that the oxidation of branched-chain amino acids, and in particular leucine, can increase significantly during intense physical activity, accompanied by a decrease in plasma levels and a reduction in muscular and athletic capacity.

This evidence paved the way for the experimentation of BCAAs in sports, allowing us to highlight some important properties, such as:

1. Antifatigue
2. MIOPROTETTIVA

Anti-fatigue properties: the first studies on this subject showed that supplementation with BCAA a few minutes before the performance could increase the time necessary for muscle exhaustion, prolong performance, and reduce the sensation of fatigue. Initially these abilities were attributed exclusively to the biochemical role of branched chain amino acids, useful in supporting the body's energy functions, while today the BCAAs' ability to significantly reduce the levels of circulating aromatic amino acids, including tryptophan, is known. of serotonin production and relative feeling of central fatigue.

In particular, the action of the branched is due to the ability of these 3 amino acids to compete with the tryptophan for the LNAA transporter present at the level of the blood-brain barrier, reducing the availability of free tryptophan and consequently the production of serotonin (neurotransmitter implicated in the mechanisms of fatigue - tiredness - aggressiveness) at central level.

Myoprotective properties: several authors, with completely independent research, have observed that supplementation with branched-chain amino acids, especially if performed before training, is able to significantly reduce the plasma levels of some markers of muscle tissue damage, such as creatine kinase or the muscular isoform of the lactic dehydrogenase enzyme. This myo-protective effect is particularly important in safeguarding the muscular structure, and exerting one of the anticatabolic effects par excellence.

L - Arginine : a conditionally essential amino acid, because although our body can synthesize it from other amino acids, such as ornithine or citrulline, it must be introduced through the diet to satisfy its daily needs.

Present in peanuts, meats and legumes, arginine is absorbed at duodenal level, and partly metabolized at an enterocyte level. Once absorbed, it reaches the various parts of the body, in particular the liver, where it supplies the urea cycle, thus ensuring ammonia detoxification. In addition to the detoxifying action, arginine is important for:

1. strengthen the immune system;
2. synthesize creatine;
3. guarantee the correct protein synthesis;
4. allow the synthesis of collagen, polyamines and proline, facilitating the reparative phenomena.

Other properties very dear to athletes of various disciplines:

• Precursor of nitric oxide: a powerful vasodilator that would allow a better flow of oxygen and nutrients at the muscular level;
• Inducer of GH secretion: which would ensure an increase in lean mass at the expense of fat.

Rationale for use - Nitric Ram - Prolabs

Although supplementation with branched chain amino acids has been tested for several years now, it is important to reiterate that there is still no consensus on the potential ergogenic effects of these products. In particular, if my protective and anti-fatigue effect seems to be the most characterized, the effect on hormonal secretion and on improving performance remains to be investigated. In this regard, it appears that BCAAs are not able to significantly improve performance, either at low or high dosages. The aspect on hormonal secretion remains somewhat doubtful, given the presence of some studies that show an increase in GH secretion following supplementation with 12 grams of BCAA and physical exercise conducted at 75% of VO2max, and in the presence of others who deny categorically these results.

Regarding arginine, the scientific literature is very skeptical about the various effects described and hypothesized, in particular on the release of GH, where there is a very high individual variability. Even more uncertain is the ability to improve performance, reducing lactate levels and the feeling of muscle fatigue, probably associated with the substrate effect on the release of nitric oxide (a powerful vasodilator) by endothelial cells.

Together, arginine and BCAAs proved effective, if taken in the immediate pre-workout (10 'before), in saving muscle from exercise-induced proteolysis conducted at 50% of maximum intensity, and in moving the plasma BCAA / tryptophan ratio verso, the branched with a consequent reduction in the synthesis of serotonin.

Recommended use by the company - Nitric Ram - Prolabs

Swallow 7 tablets a day with water or other liquid of your choice, 30-40 minutes before training or competitions.

Use in sports - Nitric Ram - Prolabs

In the common sporting practice, dosages of around 100 mg / kg are suggested, regardless of the physiological, nutritional and sporting needs of the athlete. The choice of dosage should instead be calculated based on the aforementioned variants, in particular in relation to the protein content ingested. On average, in healthy individuals who practice physical activity at an amateur level, dosages of around 83 mg / kg / day are considered to be effective, doubling in agonist athletes. The intake should be carried out on an empty stomach, in order to avoid competitive reactions in the intestinal absorption processes, approximately between 40 and 60 'before training, given the rapid but variable intestinal uptake times.

As for arginine, at dosages ranging from 2 to 8 grams / day, beneficial effects on performance were recorded, while other dosages were tested to modulate GH secretion, with disappointing results.

The product in question has well balanced doses, which are well suited to simultaneously meeting the needs of both BCAAs and Arginina. The number of tablets to be taken should be calibrated considering a dosage of 83mg / kg / day; for a 70kg man, the 7 tablets provided by the manufacturer guarantee a correct supply of branched chain amino acids and arginine at the same time.

Nitric Ram synergies - Prolabs

BCAA + Arginine: a study carried out on 8 healthy volunteers shows a significant reduction in phenylalanine levels (muscle proteolysis marker) following physical exercise preceded by integration with 2 g of BCAA and 0.5 g of arginine.

BCAA + Carbohydrates: some studies show a useful synergy to reduce the feeling of fatigue during athletic performance (potential role of BCAAs), and improve performance (energy role of carbohydrates). In the post work out, on the other hand, the BCAAs seem to improve insulin sensitivity, therefore glycogen resynthesis in the presence of CHO, while high glycemic index carbohydrates, increasing insulin secretion, can both favor the absorption of the same BCAAs and support the anabolic phase

Side effects Nitric Ram - Prolabs

The long-term side effects of a diet too rich in proteins or amino acids are well known. Renal damage, dehydration induced by increased urinary secretion, lipidemic alterations and associated pathologies, tissue acidosis and bone demineralization, are just some of the consequences of an unbalanced diet that lasts over time.

Acute BCAA ingestion appears to be well tolerated and free of side effects, even when concentrations rise to 450mg per kilogram of body mass.

Precautions for use Nitric Ram - Prolabs

The product is contraindicated in cases of renal or hepatic disease, cardiovascular disease and / or hypertension, during pregnancy, during lactation, under 12 years and for adolescents not yet trained.

In the event of prolonged use (over 6/8 weeks), medical advice is required.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of Nitric Ram - Prolabs.

BIBLIOGRAPHY

J Strength Cond Res. 2010 Apr 7. [Epub ahead of print] BCAA Supplementation Lowers Perceived Exertion But Does Not Affect Performance in Untrained Males. Greer BK, White JP, Arguello EM, Haymes EM. J Strength Cond Res. 2010 Apr; 24 (4): 1125-30. Amino acid supplements and recovery from high-intensity resistance training. Sharp CP, Pearson DR. J Sports Med Phys Fitness. 2009 Dec; 49 (4): 424-31. Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program. Matsumoto K, Koba T, Hamada K, Sakurai M, Higuchi T, Miyata H. J Nutr Sci Vitaminol (Tokyo). 2009 Jun; 55 (3): 288-91. Effects of squat exercise and amino acid concentration in young women. Shimomura Y, Kobayashi H, Mawatari K, Akita K, Inaguma A, Watanabe S, Bajotto G, Sato J. Int J Sport Nutr Exerc Metab. 2007 Dec; 17 (6): 595-607. Branched-chain amino acid supplementation and indicators of muscle damage after endurance exercise. Greer BK, Woodard JL, White JP, Arguello EM, Haymes EM. Int J Sports Med. 2007 Jun; 28 (6): 531-8. Epub 2007 May 11. Branched-chain amino acids and arginine supplementation attenuated skeletal muscle proteolysis induced by moderate exercise in young individuals. Matsumoto K, Mizuno M, Mizuno T, Dilling-Hansen B, Lahoz A, Bertelsen V, Münster H, Jordening H, Hamada K, Doi T. Med Sci Sports Exerc. 1998 Jan; 30 (1): 83-91. Branched-chain amino acids prolonged during heat stress in men and women. Mittleman KD, Ricci MR, Bailey SP. Sports Med. 1995 Sep; 20 (3): 160-88. Exercise and brain neurotransmission. Meeusen R, De Meirleir K. Amino Acids. 2001; 20 (1): 1-11. Plasma lactate, GH and GH-binding protein levels in exercise following BCAA supplementation in athletes. De Palo EF, Gatti R, Cappellin E, Schiraldi C, De Palo CB, Spinella P. J Sports Med Phys Fitness. 2000 Sep; 40 (3): 240-6. Effects of branched-chain amino acid supplementation serum creatine kinase and lactate dehydrogenase after prolonged exercise. Coombes JS, McNaughton LR. Sports Med. 1999 Jun; 27 (6): 347-58. Leucine supplementation and intensive training. Mero A. and to allow maintenance of a high level of performance. J Cell Biochem. 2010 May 12. [Epub ahead of print] Potential role of branched-chain amino acids in glucose metabolism through the accelerated induction of the glucose-sensing apparatus in the liver. Higuchi N, Kato M, Miyazaki M, Tanaka M, Kohjima M, Ito T, Nakamuta M, Enjoji M, Kotoh K, Takayanagi R. Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels. Herman MA, She P, OD Peroni, Lynch CJ, Kahn BB. J Biol Chem. 2010 Apr 9; 285 (15): 11348-56. Epub 2010 Jan 21. //jn.nutrition.org/cgi/content/full/135/6/1547S Int J Sports Med. 2007 Jun; 28 (6): 531-8. Epub 2007 May 11. Branched-chain amino acids and arginine supplementation attenuated skeletal muscle proteolysis induced by moderate exercise in young individuals. Matsumoto K, Mizuno M, Mizuno T, Dilling-Hansen B, Lahoz A, Bertelsen V, Münster H, Jordening H, Hamada K, Doi T.