About Tribulus Maximus - BIOTECH USA
Tribulus Maximus - BIOTECH USA
Food supplement based on Tribulus Terrestris
FORMAT
Pack of 90 capsules
COMPOSITION
Tribulus terrestris fruits titrated to 50% protodioscine
Capsule: Gelatin
Stabilizer: microcrystalline cellulose
Anti-caking agents: magnesium stearate
Per daily dose (2 capsules): Tribulus Terrestris 1500 mg, of which Protodioscine 750mg
Product features Tribulus Maximus - BIOTECH USA
The molecular characterization of this plant, and in particular of its fruits, has highlighted the presence of flavonoids, starches, alkaloids and saponins, each of which has different practical implications.
Among all these compounds, and others still in the individuation phase, we focused on a principle, the PROTODIOSCIN, which seems to be responsible for the anabolic-like and stimulating effects of this plant. A study conducted on animal models, rats and rabbits, has shown that this compound, belonging to the saponin family, can significantly increase the levels of luteinizing hormone (LH), dehydroepiandrosterone (DHEA), testosterone, dihydrotestosterone and increase both spermatogenesis and the frequency of the couplings.
Tribulus in sports
As already mentioned, supplements based on this plant extract are used by many sportsmen with the hope of increasing endogenous testosterone levels, supporting muscle growth and supporting the anabolic phase. With the same intent, some bodybuilders hope to be able to increase endogenous testosterone levels at the end of a doping cycle with steroid anabolic hormones, trying to minimize the side effects that this practice involves (decrease in endogenous synthesis).
Rationale - Tribulus Maximus - BIOTECH USA
Although studies on animal models have reported encouraging results, these turn out to be somewhat meaningless, when compared to those performed on humans. A known practice is in fact to broaden and generalize the effects recorded on laboratory animals, or on individuals affected by certain pathologies, to the healthy and trained human organism, regardless of the enormous interspecies and intraspecies variability. In light of the above - even considering the experimental studies conducted on animals - we will take as reference, for the evaluation of the efficacy of this product, studies that document the activity of tribulus on humans. The scientific literature shows different works in this respect:
- Study on 22 rugby athletes with 450 mg / day of tribulus for 5 weeks: no increase in lean mass, no increase in muscle strength, no difference in the urinary testosterone / epitestosterone ratio;
- Study on 21 healthy individuals subjected to supplementation with 10/20 mg / kg / day for 4 weeks: no difference in plasma testosterone, androstenedione and LH levels;
- Study on 15 healthy subjects at 3.21 mg / kg / day for 8 weeks: no change in weight and body composition.
- Study conducted on prepared athletes shows no change in blood characteristics after supplementation for 20 days with tribulus.
These and other studies allow us to draw conclusions about the inefficacy of tribulus, in endogenous testosterone stimulation in healthy humans, even at important dosages.
Recommended use by the company - Tribulus Maximus - BIOTECH USA
Swallow 2 capsules a day in a glass of water.
Use in sports - Tribulus Maximus - BIOTECH USA
The various studies seem to agree on the ineffectiveness of tribulus-based supplements, even if used at very different dosages. No result was in fact obtained at modest dosages (450mg / day) or important (20 / mg / kg / day), both for short and prolonged periods.
It is therefore very difficult to define an optimal dosage in sports, given also the absence of precise studies on its pharmacokinetics and biodistribution.
Tribulus Maximus side effects - BIOTECH USA
Fortunately, the side effects also seem to be insignificant, although there have been cases of abdominal pain. To be documented is a study that reported the presence of gynecomastia following the chronic use of tribulus terrestris.
Interactions Tribulus Maximus - BIOTECH USA
Although the pharmacokinetics of this product is not characterized, it is known that saponins can interfere with the absorption of different substances, significantly changing their bioavailability.
Among the typical effects of saponins in general we can remember the expectorant, mediated by an irritant action on the mucosa, cholesterol-lowering, anti-edema and anti-inflammatory.
Precautions for use Tribulus Maximus - BIOTECH USA
The product is contraindicated in cases of renal or hepatic disease, cardiovascular disease and / or hypertension, during pregnancy, during lactation and under 14 years.
This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of Tribulus Maximus - BIOTECH USA.
BIBLIOGRAPHY |
The effect of five weeks on elite strength and muscle composition during preseason training in elite rugby league players. Rogerson S, Riches CJ, Jennings C, Weatherby RP, Meir RA, Marshall-Gradisnik SM. J Strength Cond Res. 2007 May; 2: 134-9. Chinese. Short term impact of Tribulus terrestrial intake on doping control analysis of endogenous steroids. Saudan C, Baume N, Emery C, Strahm E, Saugy M. J Ethnopharmacol. 2003 Apr; 85 (2-3): 257-60. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Boll Chim Farm. 1998 Dec; 137 (11): 473-5. Effect of Tribulus terrestris L. saponin mixture on some smooth muscle preparations: a preliminary study.Arcasoy HB, Erenmemisoglu A, Tekol Y, Kurucu S, Kartal M. The hormonal effects of Tribulus and its role in the management of male erectile dysfunction - an evaluation using primates, rabbit and rat.Gauthaman K, Ganesan AP. Int Braz J Urol. 2007 Jul-Aug; 33 (4): 554-8; discussion 558-9. Free serum testosterone level in male rats treated with Tribulus alatus extracts.El-Tantawy WH, Temraz A, El-Gindi OD. Ann NY Acad Sci. 2006 Nov; 1084: 391-401. The protective effect of Tribulus terrestris in diabetes.Amin A, Lotfy M, Shafiullah M, Adeghate E. Breast. 2004 Oct; 13 (5): 428-30. Gynaecomastia and the plant product "Tribulis terrestris".Jameel JK, Kneeshaw PJ, Rao VS, Drew PJ. Zhong Yao Cai. 2003 May; 26 (5): 341-4. [Effect of saponin from Tribulus terrestris on hyperlipidemia]Chu S, Qu W, Pang X, Sun B, Huang X. [Hypoglycemic effect of saponin from Tribulus terrestris] Li M, Qu W, Wang Y, Wan H, Tian C. Zhong Yao Cai. 2002 Jun; 25 (6): 420-2. Chinese. Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men.Brown GA, Vukovich MD, Reifenrath TA, Uhl NL, Parsons KA, Sharp RL, King DS. Ann Acad Med Singapore. 2000 Jan; 29 (1): 22-6. Adaikan PG, Gauthaman K, Prasad RN, Ng SC. Ann Acad Med Si sett.ngapore. 2000 Jan; 29 (1): 22-6. |