supplements

ALC supplement PRO ACTION

Information on ALC supplement PRO ACTION

ALC supplement PRO ACTION (500 mg capsules).

Food supplement of acetyl L carnitine.

FORMAT

60 cps bottle, 500 mg each

COMPOSITION

Acetyl L-Carnitine hydrochloride: stable salt of the active ingredient.

Rice starch: excipient able to stabilize the active ingredient and improve absorption.

Capsule: edible gelatin.

Dye: titanium dioxide.

A CAP of ALC supplement PRO ACTION CONTAINS:
Kcal1.1
kj4.7
Protein0.085 g
Carbohydrates0.194 g
Grassi0 g
Acetyl carnitine200mg

Product features ALC supplement PRO ACTION

The described product can be considered a supplement based on acetyl-L-carnitine. In fact, as an active ingredient, we exclusively find the ALC at a dosage of 200mg per capsule. The product comes in the form of capsules of alimentary gelatin, able to make it easier to take and protect the active ingredient from possible oxidative events that would compromise its functionality. The capsule is easily digested at the gastric level and the acetyl-L-carnitine is mainly absorbed at the duodenal level (through passive diffusion and cotransport mechanisms facilitated with sodium).

ALC is the most abundant ester of the most common L-carnitine ((3R) -4-trimethylamino-3-hydroxybutyrate), mainly involved

  • in the transport of fatty acids through the mitochondrial membrane, promoting oxidation with consequent energy production,
  • in the regulation of the acetyl CoA / CoA ratio, optimizing the glucose metabolism,
  • in the similar colander function, important as an antioxidant and neuroprotective factor.

Compared to the more common L carnitine (in the form of supplement), acetyl-L-carnitine has a better absorption profile, with bioavailability levels of around 43% (estimated on doses of 2 gr / day) and achievement of the blood peak at 4h from oral administration (evaluated on pharmacological and non-integrative doses).

Potential benefits for sports use ALC supplement PRO ACTION

  • Greater efficiency of lipid oxidative metabolism
  • Optimization of glycolytic and oxidative processes of sugars, with consequent reduction of lactate (reduced sensation of post-workout muscle fatigue)
  • Muscle glycogen savings and reduced post-workout muscle fatigue
  • General antioxidant activity
  • Generalized improvement of oxidative metabolism, with consequent increase in the athlete's resistive capacity.

Recommended use by the company - ALC supplement PRO ACTION

1 cps a day in a little water.

How to use it in sports practice ALC supplement PRO ACTION

In sports, supplementation with acetyl carnitine can be up to 2 grams per day, even if more concentrated but evidently useless supplementary protocols are described.

In the case of high doses, to ensure correct absorption it would be necessary to divide the total quantity into more than about 500 mg / day intakes, for which the bioavailability levels are maximum. It is necessary not to prolong the administration beyond 4 weeks, in order to avoid a haematic accumulation of acetyl-L-carnitine, with consequent reduction of renal reabsorption and increased clearance; in other words, it would mean throwing away the product and making the kidneys work in vain.

The half-life is estimated to be around 6.5 hours.

How to optimize your business - ALC supplement PRO ACTION

The best results for sports use would certainly be those aimed at losing fat mass. It is therefore clear that the best association involves a low-calorie diet, and a mainly mild aerobic physical activity, bearing in mind that lipid transport for energy use is maximum when the glucose metabolism is reduced.

In this regard, an integrative cycle with increasing doses of ALC could be envisaged, accompanied by a gradual reduction in caloric content and in the carbohydrate content of one's diet plan.

Rationale for use - ALC supplement PRO ACTION

Numerous studies have been published in the literature regarding the metabolic and therapeutic capacities of carnitine and its acyl derivatives, but all are related to the improvement of established pathological conditions.

However, studies showing the efficacy of supplementation with acetyl L carnitine in improving athletic performance are lacking, although the literature shows the direct involvement of this molecule in skeletal muscle metabolism during physical activity, and in the reduction of total fat mass.

The limiting step of sports supplementation appears to be the ability to store muscle, although a recent study shows the increase in carnitine muscle stocks after supplementation with intravenous acetyl carnitine and controlled hyperinsulinemia, a situation very difficult to reproduce in the common supplementary practice .

Side effects ALC supplement PRO ACTION

At high doses I can experience episodes of insomnia, nausea, abdominal cramps, migraine and gastro intestinal disorders.

Precautions for use ALC supplement PRO ACTION

Contraindicated in cases of renal, hepatic, diabetic, pregnancy, lactation, mood disorders.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of ALC supplement PRO ACTION.

BIBLIOGRAPHY

Applied metabolics - vinegars l carnitine.

J Physiol. 2007 June 1; 581 (Pt 2): 431-44

New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscleFrancis B Stephens, Dumitru Constantin-Teodosiu, and Paul L Greenhaff

Ann NY Acad Sci. 2004 Nov; 1033: 30-41.

Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism Rebouche CJ.

Gastroenterology. 1986 Jul; 91 (1): 10-6.

Carnitine transport in human intestinal biopsy specimens. Demonstration of an active transport system. Hamilton JW, Li BU, Shug AL, Olsen WA.

Clin Pharmacokinet. 2003; 42 (11): 941-67.

Pharmacokinetics of L-carnitine. Evans AM, Fornasini G.

J Appl Physiol. 1988 Jun; 64 (6): 2394-9.

Influence of carnitine supplementation on muscle substrate and carnitine metabolism during exercise. Soop M, Björkman O, Cederblad G, Hagenfeldt L, Wahren J.

Carnitine for fatigue in multiple sclerosis.

Tejani AM, Wasdell M, Spiwak R, Rowell G, Nathwani S. Cochrane Database Syst Rev. 2010 Feb 17; 2: CD007280.