tumors

BRCA1 and BRCA2 genes and breast cancer: some interesting percentages

Several studies have shown that inherited mutations in the BRCA1 and BRCA2 genes have a considerable influence in determining the premature appearance of breast cancer.

Recalling that one in eight women falls ill with breast cancer sooner or later, it is estimated that the hereditary mutations of BRCA1 and BRCA2 are responsible for 20-25% of all family forms of breast cancer and 5-10% of all forms of breast cancer.

But how many women, carriers since the birth of a mutation in BRCA1 or in BRCA2, get breast cancer?

According to various studies, breast cancer would affect 55-65% of women under the age of 70 with an inherited mutation in BRCA1 and 40-45% of women under the age of 70 with an inherited mutation in BRCA2.

From the point of view of heredity, a couple in which only one element carries a mutation in BRCA1 or BRCA2 has a 50% chance of passing on the same mutation to each child.