physiology

Which anesthetic drugs cause malignant hyperthermia?

Malignant hyperthermia is a pathological condition, transmitted by inheritance, which manifests itself with an increase in body temperature and a massive muscular contraction only after the intake of certain anesthetic drugs.

But what exactly are the anesthetics that make malignant hyperthermia manifest? Which harmless ones?

The anesthetic drugs dangerous for those suffering from malignant hyperthermia are the volatile anesthetics used for general anesthesia - that is, halothane, sevoflurane, desflurane, isoflurane and enflurane - a neuromuscular relaxant called ososamametonio (or succinylcholine ) a blocker of the neuromuscular junction known as decamethonium .

Lidocaine, bupivacaine and mepivacaine local anesthetics, morphine and fentanyl opiates, ketamine, nitric oxide, propofol, etomidate, benzodiazepines and, finally, pancuronium, cisatracurium, and myorelaxants are dangerous., mivacurium, vecuronium and rocuronium.