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CE Extreme - Scitec Nutrition - Creatine ethyl ester

Information on CE Extreme - Scitec Nutrition - Creatine ethyl ester

CE EXTREME - SCITEC NUTRITION

Food supplement based on creatine ethyl ester

FORMAT

Pack of 120 capsules

COMPOSITION

Creatine ethyl ester

PER PORTION: Creatine 2 gr

Product features CE Extreme - Scitec Nutrition - Creatine ethyl ester

The product in question provides an alternative to the more common and tested creatine monohydrate. Creatine ethyl ester, in fact, is an ester of the most common creatine, which was created with the aim of improving the pharmacokinetic properties of monodirate creatine.

Despite the chemical efforts made to formulate a new form of creatine, this has proved incapable of reproducing the effects of the more proven creatine monohydrate. Limits that seem to arise from a missed increase in creatine plasma levels, and therefore from a lack of muscle accumulation.

Furthermore, the capsule formulation makes dosage modulation more difficult and the intake uncomfortable during the loading phase.

The leading experts in the field identify creatine monohydrate powder as the most effective and safe formulation.

Creatine - partly produced endogenously in the liver and in the pancreas, and partly introduced through the diet, 95% of which is concentrated in the skeletal muscle and for the remainder in the heart and brain. Penetrated inside the muscle fiber through a cotransport with sodium, creatine spreads easily to the mitochondrial intermembrane space, where it is phosphorylated by creatine kinase, in phosphocreatine.

Phosphocreatine is the high-energy molecule responsible for producing ATP during the first minute of intense physical activity. This, in fact, can transfer the phosphate group to the ADP, guaranteeing the formation of ATP necessary to support the muscular contractile function.

Creatine thus originated will again be able to spread in the mitochondrial intermembrane space and start a new cycle. This specific energy storage system allows the body to maintain high levels of ADP, accelerating energy flow, and reducing the presence of free ATP, which would negatively affect different metabolic pathways. During this process, however, a small amount of phosphocreatine - around 2% of the total pull (about 2 grams) - is metabolised to creatinine through a non-enzymatic hydrolysis process, and irremediably excreted in the urine. The lost quota, therefore, also represents the daily requirement of creatine, which inevitably increases for athletes, and which is partly satisfied by endogenous synthesis (about 1 gr / day) and partly by dietary intake.

Rationalization of integration in sports CE Extreme - Scitec Nutrition - Creatine ethyl ester

The pro-energetic role and the high muscular tropism make creatine one of the most studied and characterized supplements in the scientific world, and one of the most used by athletes of various disciplines. The effects of a correct supplementary protocol take the form of:

  1. Improvement in strength and maximum power;
  2. Improvement of the sub-maximal exercise;
  3. Generalized improvement of anaerobic performance (measured by different methods);
  4. Increase in critical power (ie the maximum power exerted before the feeling of fatigue occurs);
  5. Reduction of myalgic fatigue;

Most of the recorded data, therefore, lean towards an efficacy of action particularly concentrated on maximal power and anaerobic performance.

However, recent studies are also highlighting other potentially important effects, oriented towards improving aerobic capacity. In fact, works are known in which there was a significant increase in the ventilatory capacity of the subject or an increase in the ventilatory treshold, although unfortunately these are not accompanied by an improvement in aerobic performance.

In conjunction with these effects, it seems that creatine supplementation can also guarantee a significant increase in lean mass, as long as it is associated with an intense training cycle. In fact, it has been demonstrated that the muscle pull of creatine tends to increase especially in the muscular regions subjected to training. The increase in lean mass, which according to some would be explained by a greater call of intracellular water, while for others through muscle hypertrophy induced by biomechanical factors (greater intensity of training) or hormonal ones (increase in IGF1 levels), could, as can be seen from some studies, invalidating the performance especially for sports such as cycling or the marathon.

Another important action that remains to be characterized is the myoprotective effect, highlighted in some studies with a significant reduction in creatine kinase plasma levels and with a decrease in lactate dehydrogenase activity.

To conclude, it must always be remembered that the great variability of the results obtained reflects the development of integrative strategies and different evaluation protocols, but above all the great individual variability.

Recommended use by the company - CE Extreme - Scitec Nutrition - Creatine ethyl ester

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Use in sports CE Extreme - Scitec Nutrition - Creatine ethyl ester

Integration protocols for creatine monohydrate are very well characterized. The very few studies regarding creatine ethyl ester, on the other hand, seem to reproduce and suggest the same dosages as that of monohydrate, but as mentioned at the beginning of the article without reproducing the same effects. So also in this case it will be possible to suggest the intake preferably with carbohydrates and proteins, in doses not exceeding 5 grams at a time of creatine, according to different schemes that foresee or not the loading phase. This phase, characterized by the intake of 20 g / day (divided into 4 5-gram intakes) or 0.3 g per kg of lean mass / day for at least 6 days, allows to increase the phosphocreatine muscle pull of a value between 20 and 40%, depending on the nutritional status of the subject, which can then be maintained with 3 grams / day.

Alternatively it would be possible to skip the loading phase, and achieve the same result in a more gradual manner, with daily administration of 3 grams per day for about 28 days.

However, there is no lack of studies in the literature which show yet different dosages, but which do not enjoy a statistically significant series. It should always be remembered that creatine supplementation should not exceed four weeks and should be followed by a washout phase of at least 6 weeks.

CE Extreme synergies - Scitec Nutrition - Creatine ethyl ester

Carbohydrates + Creatine: taken in the hour before the race they guarantee an important energy support. Furthermore, creatine muscle uptake appears to be significantly enhanced by insulin released following carbohydrate intake, with an increase of more than 60% compared to that obtained with creatine alone.

Some evidences also show an increase in the levels of the glucose transporter GLUT 4, on muscle tissue following the intake of creatine, with an increase in glycogen resynthesis capacities; this action could be used in the post-workout anabolic window.

Carbohydrates + creatine + proteins: guarantees an increase in absorption comparable to that present only for simple carbohydrates. In this case, however, there would be a potential advantage both on the nutritional intake of the snack and a reduction in the potentially glycemic peak.

CLA + creatine + protein : at the doses of 6 g, 9 g and 36 g, respectively, taken for 5 weeks, it has been shown to be effective in improving strength and increasing muscle mass by 3 - 4% in combination with strength training.

Arginine + Creatine : seems to provide a better ergogenic boost with an increase in the maximum force peak.

Side effects CE Extreme - Scitec Nutrition - Creatine ethyl ester

Several studies agree that creatine supplementation is safe in healthy individuals. In particular, studies relating to chronic supplementation (3-5 g / day for one year) and acute (20 g / day for a week) do not show any particular side effects.

However, it should be remembered that ingesting too high or poorly solubilized doses could be accompanied by abdominal cramps, nausea, vomiting and diarrhea, as well as chronic doses, especially if performed concomitantly with high-protein diets could significantly increase renal load.

Finally, even if it does not represent a real side effect, it must be considered that the increase in weight that derives from the accumulation of water inside the cell, could have a negative impact on performance.

Precautions for use CE Extreme - Scitec Nutrition - Creatine ethyl ester

The product is contraindicated in cases of renal or hepatic disease, cardiovascular disease and / or hypertension, in pregnancy, during lactation and under 12 years and adolescents not yet trained.

In the event of prolonged use (over 6/8 weeks), medical advice is required.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of CE Extreme - Scitec Nutrition - Creatine ethyl ester.