What is piperine?
Piperine is the alkaloid characteristic of black pepper, which contains it in concentrations ranging from five to eight percent by weight. Just the generous content of piperine, and of its cavacina isomer, is responsible for the typical spicy and pungent taste of traditional pepper ( Piper nigrum ) and the long one ( Piper longum ).
Properties and Uses
The ability to increase salivary and gastric secretion is ascribed to piperine, stimulating digestion and improving the intestinal absorption of many nutrients and phytochemicals, such as coenzyme Q10 and beta-carotene. Piperine also appears to be able to accelerate intestinal transit times, and exhibits antioxidant properties in vitro.
The recent discovery that topical application of piperine can stimulate skin pigmentation, especially following irradiation with UVB rays, has made this substance quite popular in products dedicated to the treatment of vitiligo.
Let us remember, for completeness, that piperine is a traditional component of Ayurveda, an ancient Indian medicine based on a profound knowledge of the body and its relationship with the mind and the spirit. Ayurvedic medicine therefore considers health as a state of equilibrium in which psychological and environmental factors have the same importance as physical ones.
Mode of use
The typical intake dosage is 5 mg of piperine per day, with the recommendation not to exceed 15 mg / day.
Piperina supplements online
Online it is possible to find Piperina Forte with Chromium Picolinate, which improves the metabolism of the body thanks to the stimulation of the histamine receptor (H22), which, in turn, increases the secretion of intestinal, gastric and pancreatic juices, improving absorption. of food. The supplement is formulated with 95% black pepper extract: the high concentration of active ingredient ensures a direct action on weight and body fat control. It also contains Picolinate Chrome, useful for appetite control. Remember that natural supplements should not be used as a meal substitute, but as a complement to a balanced diet and constant physical activity.
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Alternatively, you can opt for a supplement that associates Piperina and Curcuma, providing for each capsule 350 mg of Curcumin turmeric and 7 mg of Piperina black pepper of 95%. This balanced dose of piperine not only increases the medicinal virtues of curcumin, but also naturally increases its bioavailability while maintaining excellent digestive tolerance. The manufacturer suggests the use of this supplement to relieve joint pain, inflammation and digestive disorders, as a complement to detox diets, to strengthen and protect the body and, thanks to the antioxidant properties of curcumin, to counteract aging.
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Side effects
Contraindications and drug interactions
The user of piperine based supplements should remember that this substance, if taken by mouth, is able to increase the blood concentration of theophylline (bronchodilator), phenytoin (antiepileptic), propranolol (B-blocker) and curcumin (up to 2000%). This effect is mainly related to the demonstrated ability to inhibit hepatic glucuronidation, a fundamental reaction for their metabolism in inactive substances and subsequent excretion. Finally, piperine is traditionally contraindicated in the presence of gastritis, gastroesophageal reflux, gastric ulcer, hemorrhoids and hypertension.
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