AAKG - Scitec Nutrition - Arginine α-ketoglutarate

About AAKG - Scitec Nutrition - Arginine α-ketoglutarate

Arginine α-ketoglutarate food supplement

FORMAT

100 cps bottle

COMPOSITION

Argininaα-ketoglutarate

Stabilizer: microcrystalline cellulose

Anti-caking agents: Magnesium stearate

One dose (3 capsules) contains: Arginine α-ketoglutarate 1600 mg

Product features AAKG - Scitec Nutrition - Arginine α-ketoglutarate

Arginine α-ketoglutarate 1600 mg - this product comes in the form of arginine salt, in which two arginine molecules are associated with one of alpha keto glutarate. Arginine is a semi-essential amino acid for humans; in fact the organism is able to synthesize it endogenously in case of deficiency. The intense physical activity, however, seems to increase the need for this amino acid, which can however be integrated simply with a healthy diet, given that it is easily found in products of animal origin, and in some vegetables such as peanuts. A balanced diet, in fact, is able to make 4 to 6 grams of arginine a day, a quantity that is satisfactory for most individuals. Arginine is essential in numerous biological reactions; in fact it is part of the urea cycle (facilitating the elimination of waste products deriving from the amino acid oxidation), it is a glucogenic amino acid (therefore it is able to supply the body with glucose in the event of energy deficiency), it has a plastic function (re-enters protein synthesis), and participates in the metabolism of endothelial-derived nitric oxide.

Alpha ketoglutarate is a very important metabolic keto acid, as it represents a crossroads between catabolic and anabolic reactions. This molecule is part of the krebs cycle, thus favoring the production of energy, but it is also part of the gluconeogenic process, allowing the synthesis of glucose starting from non-carbohydrate sources such as amino acids; finally it is also part of the synthesis of some amino acids such as glutamate (therefore glutamine), proline and arginine. However, there are numerous studies that are testing the potential of this ketoacid, with important results relating to the possibility of preserving the protein component in patients suffering from kidney disease, reducing urinary nitrogen secretion, and improving the conditions of patients suffering from intestinal diseases and collagen synthesis in elderly patients, with consequent prevention against certain diseases such as osteoporosis, atherosclerosis and arthritis. We are still investigating its direct ability to inhibit cell proliferation and to act in the regulation of cellular functionality in a similar way to a hormone.

Use in sports AAKG - Scitec Nutrition - Arginine α-ketoglutarate

For some time now, various sportsmen have been using arginine alpha-ketoglutarate in the hope of achieving the following results:

1. Increased growth hormone release;
2. Increased lean mass;
3. Better sports performance;
4. Increase in resistive capacity and maximum force.

These objectives are subtended by the observed biological effect and in particular by the involvement of this amino acid in the synthesis of nitric oxide.

This powerful biological mediator, in fact, promoting vasodilation, should facilitate the supply of oxygen and nutrients to the muscular level, allowing athletic performance to be sustained longer and more intensely. Furthermore, nitric oxide also appears to be involved in numerous intracellular communication pathways, which could lead to the release of a number of hormones.

The metabolic effects of arginine and alpha ketoglutarate may also be useful in energetically supporting the cell, and in improving the muscle recovery phase by preserving from proteolysis and increasing protein synthesis.

Rationale for use: what is proven - AAKG - Scitec Nutrition - Arginine α-ketoglutarate

Despite, in theoretical terms, this ergogenic action could be conceivable, the data present in scientific literature are somewhat discordant and opposed, harboring false hopes.

• GH release : the literature seems to agree on the effect inducing the release of GH by arginine in individuals with secretory deficits or following massive intravenous administration.

Rather discordant are the studies on the effects related to the function of secretagogue for GH, of orally taken arginine. Some, in fact, believe it can increase GH levels, while others argue that it may even reduce the potential release that would be obtained as a result of physical performance alone.

From the various studies, therefore, a large individual variability emerges to the response, which certainly bears its own genetic heritage.

• Metabolic / energetic effect : numerous studies seem to agree that oral supplementation with arginine and alpha-ketoglutarate can sustain athletic performance, highlighting a delay in the onset of anaerobic metabolism, an increase in peak force and greater resistance to physical exercise.
• Change in body composition : Almost all studies agree that oral arginine supplementation does not affect the change in body composition in men. The opposite is instead supported by a study carried out on obese rats.

Recommended use by the company

Swallow 3 capsules a day with water or other liquid of your choice, 20-30 minutes before meals or before bedtime, on an empty stomach.

Use in sports - AAKG - Scitec Nutrition - Arginine α-ketoglutarate

In studies where positive results have been obtained in improving athletic performance, generally the administration of arginine varies between 2 and 8 grams per day.

A study, instead, carried out on the arginine alfachetoglutarato, suggests a dosage of 12gr daily divided into 3 dosages for 8 weeks (dosage to which side effects may be recorded).

However, administration on an empty stomach remains valid, to avoid competitive effects in absorption.

Administration of arginine before going to bed is justified by a study ONLY which shows that oral intake of 250 mg / kg of arginine aspartate before bedtime can increase GH levels by 60%.

How to optimize its activity - AAKG - Scitec Nutrition - Arginine α-ketoglutarate

Studies show that the simultaneous administration of creatine and arginine can determine a better ergogenic boost, with a relative improvement in muscular endurance and maximum peak strength.

At the same time, the intake of arginine and antioxidants appears to increase the anaerobic threshold by 16%, delaying the feeling of fatigue.

Another possible association is with branched chain amino acids; in fact, a study shows that the supplementation of 2 g of BCAA with 0.5 g of Arginine, can reduce proteolysis following intense muscular exercise.

Side effects AAKG - Scitec Nutrition - Arginine α-ketoglutarate

The most common side effects, recorded in large doses, are vomiting, diarrhea and abdominal cramps at doses above 9 grams per day.

Massive doses, generally higher than 30 g, can originate nephrotoxicity, hypotension and headaches.

Precautions for use AAKG - Scitec Nutrition - Arginine α-ketoglutarate

The product is contraindicated in cases of renal or hepatic disease, cardiovascular disease and / or hypertension, in pregnancy, during lactation and under 12 years and adolescents not yet trained.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of AAKG - Scitec Nutrition - Arginine α-ketoglutarate.