The skin, or skin, is a continuous fabric, belonging to the integumentary system. It is composed of three main layers which, from the outside towards the inside, take the name of: epidermis, dermis and hypodermis (or subcutaneous layer).

The human body has an area of ​​between 1.5 and 2 m2 approximately. Considering an average thickness of the superficial layers of 2-3 mm, the total weight of the skin can be evaluated in the order of 10 Kg. This implies that, after skeletal musculature, the skin is one of the major organs for extension and weight (15% of body weight).

The skin has two fundamental and extraordinary properties: self-repair (regenerates itself following a lesion) and extensibility (it adapts perfectly to the variations in body size that occur over the course of a lifetime).

The skin performs numerous and very important functions:

  • protects us from trauma, ultraviolet radiation, microorganisms and chemical agents.
  • Prevents the loss of liquids; if for example a burn causes the destruction of a tenth of the skin surface, the loss of liquids and electrolytes can lead to deadly consequences.
  • Participates in the mechanism of thermoregulation, taking advantage of the intervention of sweat glands and the ability to regulate blood flow, increasing (vasodilation) or slowing (vasoconstriction) heat dispersion. The hypodermis, the deepest layer of the skin, retains more heat as its lipid thickness increases; for this reason overweight people suffer most from the summer heat.
  • Coordinates the immune response against tumors and pathogens.
  • The skin has metabolic properties, since the synthesis of vitamin D occurs precisely at the skin level. The skin is also an important lipid reserve.
  • The skin also has a very important sensory function: with its most superficial layer it registers and transmits pressure (tactile), painful and thermal stimuli, while with the deeper one it also perceives thermal and vibratory signals.

Insights

The epidermis

Histological and functional organization of the five layers that make it up

Differentiation of keratinocytes

Cell renewal of the epidermis: what it is, how it happens, what is affected by it

Skin and dehydration

The skin is an effective protective barrier against dehydration, we see this precious feature in detail

corneocytes

bodies of Odland

natural factor

of hydration

Hydroplipidic film and epidermal lipids: how they are produced, what functions they cover and why they are so important for the health of our skin

Skin colour

and melanin

What does skin color depend on? What are the functions of melanin?

Changes in skin color

What is the significance of the various spots, clear, dark and in relief present on our skin?

Solar radiationSun exposure and dangers to skin and health
The dermisIt is the middle layer of the skin, in this article we examine its histological and functional characteristics.
hypodermis

It is the deepest layer of the skin, a connective tissue consisting of a scaffold of connective fibers, between whose meshes lipid clusters are inserted. Interesting insight into white and brown adipose tissue

Sweating

Apocrine Giandole

Sebaceous glands

In the skin we find three types of glands: sweat, apocrine and sebaceous. Each of them has a very precise functional meaning, let's see which (with interesting references to acne and seborrhea)

Hair follicles

Hair and hair

The nails

They are part of the skin appendages and have particular functions that we will examine briefly after having grasped their histological characteristics

Skin aging

Skin aging is an inevitable biological phenomenon, understanding its causes can help slow it down

DermatitisUnder the term dermatitis there are various skin diseases, mostly characterized by inflammatory phenomena.
Dry skinThe problem of dry skin and the strategies to solve it
Oily skinThe problem of oily skin and the strategies to solve it
Nickel: nickel allergy

Nickel allergy is the most common cause of allergic contact dermatitis, a disease that produces skin lesions very similar to those of eczema.

Patch test

The patch test is a test used for diagnostic purposes to identify those substances that, once placed in contact with the skin, determine a local inflammatory reaction.

Goose bumps

Goose skin or anserine skin is characterized by the transient appearance of small skin reliefs close together; these very small hillocks are formed by the reflex contraction, therefore involuntary, of the erector muscles of the hair.