C vitamin
Vitamin C, or more correctly Ascorbic Acid, is a water-soluble molecule that performs many essential functions: among these it seems that the ability to prevent and reduce the symptoms of the common cold has been recognized; the topic is still controversial.
Vitamin C is an enzymatic cofactor of hydroxylation and allows the formation of collagen, adrenaline and aromatic compounds in the liver.
Cold Prevention
For about 50 years the scientific community has split into two in assessing the clinical utility of vitamin C in the treatment and prevention of the common cold. Briefly summarizing the most significant discoveries it is possible to define that:
- Vitamin C is an essential molecule to leukocyte homeostasis, therefore, its deficiency would significantly affect the immune defenses, which would be less stimulated and less active.
- some trials have shown that the pharmacological administrations of vitamin C can FIGHT the symptoms of the cold (L. Pauling 1970) and also PREVENIRNE the onset (H. Hemilia 1994-1995-1997).
- through the administration of 1-4g / day (about 200-800% of the recommended ration), it should be possible to reduce the symptoms of the common cold by 23%, and prevent its occurrence in 30% of cases (especially in subjects characterized by a strong oxidative stress).
Furthermore, it is important to point out that (quoting LARN):
At high doses of vitamin C, such as those taken for pharmacological purposes (10 or more g / day), gastrointestinal disorders have been found, but these seem to be due more to acidity than to vitamin C itself, as salts buffered no longer give the same effect. Other effects have also been reported, such as increased urinary oxalate excretion and the formation of kidney stones. However, it seems that doses up to 10g / day can be considered safe (Flodin, 1988).
However, the use of vitamin C against colds is still the subject of numerous discussions, therefore, until a compromise is reached between therapy and the maximum recommended dose, it is strongly discouraged the supplementary or pharmacological abuse in the fight against symptoms and prevention. of the common cold
Bibbliografia:
- Recommended Nutrient Intake Levels for the Italian Population (LARN) - Italian Human Nutrition Society (SINU)
- L. Pauling - Vitamin C and Common Cold - 1970
- Harri Hemila 1994; Harri Hemila 1995; Harri Hemila 1997
- NW Flodin - Pharmacology of Micronutrients - (1988) Wiley, New York
- Robert Cathcart - Vitamin C, Titrating To Bowel Tolerance, Anascorbemia, and Acute Induced Scurvy - Orthomed, 1994
- S. Hokama, C. Toma, M. Jahana, M. Iwanaga, M. Morozumi, T. Hatano, Y. Ogawa (2000 Winter). Ascorbate conversion to oxalate in alkaline milieu and Proteus mirabilis culture - PMID 11156698
- LK. Massey, M. Liebman, SA. Kynast-Gales (July 2005) - Ascorbate increases human oxaluria and kidney stone risk - J Nutr 123 (7): 1673. PMID 15987848
- Prevent and treat colds with natural remedies - R. Sahelian, V. Dolby Toews - new - chap.3 - pag 21:32.
