Definition
Prostatitis is an inflammatory process affecting the prostate, a gland located below the male bladder responsible for producing prostatic fluid (important for male reproductive function).
Causes
Some aetiological factors responsible for prostatitis still remain the object of study; however, bacterial infections certainly play a fundamental role in the appearance of many types of prostatitis.
Assumed risk factors: cystitis, compression of the prostate by other tissues, immune deficiencies, stress, localized trauma, urethritis
Symptoms
The onset of prostatitis is often abrupt and acute, and is accompanied by diffuse chills, difficulty in urinating, dyspareunia, pain during ejaculation and defecation, pain localized in the prostate, slow and painful emission of urine, blood loss with urine and rectal tenesmus. Among the most feared complications, we mention: epididymitis, orchitis, bacteremia (in the case of bacterial prostatitis).
Diet and Nutrition
Information on Prostatitis - Prostatitis Drugs does not intend to replace the direct relationship between health professional and patient. Always consult your doctor and / or specialist before taking Prostatitis - Prostatitis Drugs.
drugs
Unfortunately, therapy for the treatment of prostatitis is not always simple and immediate; often the disease requires pharmacological treatment for many weeks, taking advantage of antibiotics / antibacterials capable of penetrating deeply into the prostate tissue.
The following are the classes of drugs most used in prostatitis therapy, and some examples of pharmacological specialties; it is up to the doctor to choose the most suitable active ingredient and posology for the patient, based on the severity of the disease, the health of the patient and his response to treatment:
Quinolones
- Ciprofloxacin (eg. Ciprofloxac, Samper, Ciproxin, Kinox): penetrates deep into the prostate tissue, therefore it is the drug most used in the treatment of prostatitis. Particularly effective in the case of chronic bacterial prostatitis, the drug should be administered at a dose of 500 mg orally every 12 hours for 28 days, unless further medical indications are given.
- Levofloxacin (eg Levofloxacin, Tavanic, Aranda, Fovex): in the case of chronic bacterial prostatitis, it is recommended to administer 500 mg of active ingredient orally per day, for 28 days.
- Ofloxacin (eg. Exocin, Oflocin): it is recommended to take one 300 mg tablet of medication every 12 hours for about six weeks, as prescribed by your doctor.
In general, in the acute form 10-14 days of antibiotic therapy are needed, while the chronic forms need longer periods (4-8 weeks)
Broad- spectrum cephalosporins
- Cephalexin (eg Keforal, Cefalexi, Ceporex): the drug should be taken orally at a dose of 500 mg every 6 hours for 14 days.
Alternatively, it is possible to take other broad-spectrum antibiotics such as Cefuroxime (eg Cefoprim, Tilexim, Zoref, Zinnat) , Cefotaxima (eg Cefotaxima, Aximad, Lirgosin) , Gentamicin (eg Gentamicin, Ciclozinil, Genbrix, Gentalyn): the posology and duration of treatment of these drugs must be established by the doctor based on the patient's medical history.
Macrolides : these drugs are indicated in cases of concomitant prostatitis and chlamydial infection (the direct correlation between prostatitis and chlamydia has not yet been fully demonstrated):
- Azithromycin (eg Azithromycin, Zitrobiotic, Rezan, Azitrocin): it is recommended to take 500 mg per day for 3 days a week, for three weeks.
Tetracycline
- Doxycycline (eg Doxicicl, Periostat, Miraclin, Bassado): it is recommended to administer 100 mg twice a day for 4 weeks.
- TETRACYCLINE (eg Tetrac, Pensulvit, Ambramycin): it is recommended to take 500 mg of active ingredient orally every 6 hours, for a period varying from 3 to 7 days depending on the nature of the infection.
Sulfonamide antibiotics
- Trimethoprim (eg Bactrim): the duration of antibiotic therapy is around 10-14 days, depending on the severity of the disorder. It is recommended to administer 100 mg of drug per os every 12 hours; alternatively, take 200 mg every 24 hours. However, trimethoprim is not the drug of choice for prostatitis treatment.
Antibiotic drugs are effective only in the case of bacterial prostatitis: they are therefore not indicated in the treatment of non-inflammatory abnormal prostatitis and in asymptomatic forms.
Urinary antispasmodics
- OXYBUTININ (ex. KENTERA): drug of choice to release the smooth muscles of the areas affected by prostatitis (reduction in the frequency of bladder contractions). Particularly useful in case of urinary incontinence associated with prostatitis: start therapy with 5 mg of drug 2-3 times a day (syrup or immediate release tablets). Alternatively, take 5 mg of the substance once a day, formulated as prolonged-release tablets. A transdermal application is also possible: 3.9 mg a day, twice a week.
Anti-inflammatory drugs: the use of anti-inflammatory drugs in treatment for prostatitis is controversial. Some reports in favor of the use of Nimesulide (eg Nimesulide, Antalor, Aulin) are reported in the literature. Consult your doctor.
Alpha blockers: are drugs to be used with caution for the treatment of prostatitis, since they can generate a significant reduction in blood pressure (hypotension)
- Terazosin (eg. Ezosine, Terazosin, Prostatil, Itrin): start the therapy by taking 1 mg of the drug once a day, preferably at breakfast. Maintenance dose: increase the dosage gradually to 2 mg, 5 mg, 10 mg, once a day, in order to improve the patient's clinical profile.
- Tamsulosina (eg Tamsulosina, Omnic, Pradif, Probena): it is recommended to administer 0, 4 mg of the drug per day, half an hour after the main meal, approximately always at the same time.
- Silodosin (eg UROREC, SILODYX) is recommended to take one capsule (8 mg) per day. Particular attention should be paid to patients with prostatitis with kidney problems: in these cases, the recommended dose should be reduced by half. This drug is not recommended for patients with prostatitis accompanied by severe kidney failure.
