FUCICORT ® Betamethasone + Fusidic Acid

FUCICORT ® is a drug based on Betamethasone + Fusidic Acid

THERAPEUTIC GROUP: Active corticosteroids associated with antibiotics

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications FUCICORT ® Betamethasone + Fusidic Acid

FUCICORT ® is indicated in the treatment of eczematous dermatitis and skin diseases complicated by bacterial superinfections sustained by germs sensitive to fusidic acid.

Mechanism of action FUCICORT ® Betamethasone + Fusidic Acid

FUCICORT ® is a medicinal specialty that combines two very important active ingredients, with different and complementary therapeutic activities that are particularly useful in the treatment of cutaneous inflammatory lesions complicated by bacterial superinfections. Fusidic acid is in fact a broad-spectrum antibiotic, particularly effective against Gram-positive bacteria and in particular Staphylococcus aureus, Propionibacterium acnes and Corynebacteria, germs generally responsible for bacterial skin super-infections, while Betamethasone valerate is a classic active corticosteroid for topically, able to control cellular events responsible for the secretion of inflammatory cytokines and at the same time to significantly reduce the recruitment of inflammatory cells. The aforementioned mechanisms of action result mainly in the reduction of the inflammatory entity of the lesion and in the inhibition of the bacterial proliferation mechanisms, thus guaranteeing a prompt remission of the symptomatology, in the face of an excellent tolerability.

Studies carried out and clinical efficacy

CORTICOSTEROIDS / ANTIBIOTICS IN THE TREATMENT OF eczema SEVERO J Drugs Dermatol. 2012 Jul; 11 (7): 861-4.

Study demonstrating how the use of corticosteroid / antibiotic-based creams can guarantee a clear and rapid improvement in the symptoms associated with severe and moderate eczema, given the important role of Staphylococcus colonization in such circumstances

FUCICORT IN THE TREATMENT OF ATOPIC DERMATITIS Acta Derm Venereol. 2007; 87 (1): 62-8.

Study that demonstrates the effectiveness of Fucicort in determining a regression of the symptomatology complained of by a patient suffering from atopic dermatitis in just two weeks of treatment, resulting among other things very well tolerated and without clinically relevant side effects.

TOPIC POST-LASER THERAPY J Cosmet Laser Ther. 2012 Jun; 14 (3): 145-9. doi: 10.3109 / 14764172.2012.682066.

Study demonstrating the efficacy of topical corticosteroid treatment following laser treatment in determining a significant reduction in hyperpigmentation that is observed in these cases.

Method of use and dosage

FUCICORT ® Cream for cutaneous use with 2% of Fusidic Acid and 0.1% of Betamethasone Valerate. Generally, always according to medical indications, two or three applications per day of the appropriate amount of cream are recommended, until remission of the symptomatology.

Warnings FUCICORT ® Betamethasone + Fusidic Acid

FUCICORT ®, like other corticosteroid drugs for topical use, meets the same precautions and the same warnings for use. Therefore the doctor should inform the patient about the potential risks of the therapy and about the main warnings to be used in order to limit the incidence of side effects and maximize the effectiveness of the therapy itself. More precisely, the patient should avoid contact of the drug with eyes and mucous membranes, avoid extending the application to large regions, avoid prolonging the therapy beyond what is necessary, consult your doctor following the appearance of side effects and keep the drug out from the reach of children.

PREGNANCY AND BREASTFEEDING

The absence of clinical trials able to best characterize the safety profile of the active ingredients of FUCICORT ® for fetal health and the little encouraging experimental evidences extend the aforementioned contraindications to use also to pregnancy and the subsequent period of breastfeeding .

Interactions

At the present time, known pharmacological interactions are not known, although it should be remembered that the simultaneous intake of cytochrome inhibitor drugs may increase blood concentrations of the amount of corticosteroid absorbed.

Contraindications FUCICORT ® Betamethasone + Fusidic Acid

The use of FUCICORT ® is contraindicated in patients who are hypersensitive to the active ingredient or to one of its excipients, in patients suffering from inadequately treated viral, bacterial and fungal infections, from rosacea and perioral dermatitis.

Undesirable effects - Side effects

The use of FUCICORT ®, especially if prolonged over time or if carried out by sensitive patients, could lead to the appearance of local side effects such as erythema, contact dermatitis, hypertrichosis, skin atrophy, striae and telangiectasia. Fortunately the side effects worthy of note are rarer.