Carnosine G1F - Keforma

Information on Carnosine G1F - Keforma

CARNOSINE G1F - KEFORMA

Food supplement based on L-carnosine

FORMAT

Pack of 50grams

COMPOSITION

L-carnosine

Glucose 1 phosphate

Product features Carnosine G1F - Keforma

NUTRITIONAL INFORMATION
	100 g	dose
Energy value
Kcal / Kj Protein Grassi Carbohydrates Glucose 1 phosphate L-Carnosine	160/680 absent absent 20 g 60 g 20 g	4/17 absent absent 0.5 g 1.5 g 0.5 g

L-Carnosine - also known as beta-alanin L-histidine, is partly synthesized by the liver and partly introduced through foods of animal origin. It is estimated that the amount of carnosine introduced daily, in a diet that includes at least an animal source, is between 50 mg and 250 mg, considering that 100 grams of beef provide about 124 mg of carnosine. This dipeptide is absorbed intact in the intestine, through a specific transporter, and from here distributed to the various tissues, in which it can be metabolized by enzymes known as carnosinase, or accumulated and used for its biological properties, which are performed above all at the level of skeletal muscle and brain.

Experimental evidence suggests a key role of this molecule in controlling the body's acid / base homeostasis and in controlling oxidative damage, so much so that it has been identified as an anti-aging agent. Today it is used in different clinical trials, for the prevention of neurodegenerative diseases such as Parkinson's and Alzheimer's, for the neuropathies associated with diabetic disease, for the prevention of ROS-induced diseases (oxygen free radicals) and to reduce the risk cardiovascular. However, studies still in the experimental phase test the potential anti-neoplastic role.

Due to its biological properties, and to some experimental evidences that have shown a particular accumulation in the muscles of subjects subjected to intense training such as bodybuilders, it has also been proposed for use in sports, with the main objective of supporting athletic performance and reduce the feeling of fatigue. Both of these benefits derive from the role of the two amino acids that make up carnosine: the histidine that could assist the buffering action and anti free radicals, preserving the muscle from oxidative damage, and beta alanine, which could restore muscle glucose stocks by supporting energetically the performance. To date, there are no clear studies showing the real mechanism of action of carnosine.

Glucose 1 phosphate: central is the role of glucose in energy metabolism, representing one of the main sources of sustenance of the organism.

The phosphorylated form in position 1, the one present in this integrator, is important in regulating the glycosidic flow towards glycogen synthesis. In fact, at the muscular and hepatic level, glucose 6 phosphate is converted into glucose 1 phosphate by phosphoglucomutase, thus preventing the progression of glycolysis. In this way glucose 1 phosphate, through a series of biochemical steps, is bound to UDP, forming UDP-glucose, necessary for the formation and structuring of glycogen. Glycogen will then be broken down during exercise or fasting in order to obtain the glucose molecules needed to keep the energy flow active.

Rationale for Carnosine G1F - Keforma use

Numerous studies have highlighted a series of benefits deriving from the use of carnosine in sports. In most cases, these are benefits in terms of ergogenicity, with an increase in maximum strength, average strength and aerobic capacity. But there is no lack of studies in which there has also been an increase in muscle mass.

The mechanism of molecular action has not yet been elucidated, but it is thought to be due to the buffering action on the one hand, which prevents acidosis and supports muscle contraction, and the glucogenic effect on the other, which definitely improves the properties energetic of the muscle. A study should be mentioned in which it was observed that the administration for 3 days of carnosine guaranteed an increase of 2, 3 diphosphoglycerate, with a general improvement in aerobic capacity.

The presence of glucose 1 phosphate, should support the recovery and accumulation of muscle glycogen, thus allowing an increase in energy capacity and support of athletic performance.

Recommended use by the company - Carnosine G1F - Keforma

Dissolve one scoop (2.5 g) of product in 200 ml of water.

Mode of use in sports practice Carnosine G1F - Keforma

The use of this supplement in sports has been supplanted for a while now by beta alanine, which is cheaper and still effective in restoring carnosine muscle stocks. However currently various dosages are used, ranging from 500mg to several grams per day.

Generally it is advisable to subdivide the intake in small doses, in order to avoid blood hydrolysis and renal excretion, making the product more available for accumulation. The presence of glucose 1 phosphate also suggests intake with simple sugars, in order to use the relative insulin peak to increase the muscle uptake of carnosine, and of the same glucose 1 phosphate, promoting glycogen synthesis.

Given the powder form of this supplement, it may be useful to divide the 500mg into two 250mg dilutions in fruit juice. A protocol in which 3 days of performance can be used higher dosages, even up to 1500mg are described.

How to optimize its activity - Carnosine G1F - Keforma

As described for beta alanine supplements, synergy with creatine has been shown to be particularly useful both in improving ergogenic and anabolic properties, recording a significant increase in muscle mass in various studies. In addition, creatine has proved useful in increasing the muscular stocks of carnosine, albeit transiently.

The synergy with antioxidants such as vitamin E, glutathione, selenium and lipoic acid could also be particularly effective in counteracting the damage induced by intense physical exercise with an improvement in the recovery phase.

Side effects Carnosine G1F - Keforma

There does not appear to be any toxic effects associated with carnosine, especially when it is consumed at doses comparable to those that would be obtained with a healthy diet.

Doses higher than 500mg, used in antitumor experiments, have proved equally safe.

In experimental models even at doses of 50mg / kg no side effects were recorded.

However, long-term clinical trials are lacking.

Precautions for use Carnosine G1F - Keforma

The product is contraindicated in cases of renal or hepatic disease, cardiovascular disease and / or hypertension, during pregnancy, during lactation and under 14 years.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of Carnosine G1F - Keforma.

BIBLIOGRAPHY

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