RECAL ® - Calcium carbonate

RECAL ® is a calcium carbonate drug

THERAPEUTIC GROUP: Mineral supplement: calcium carbonate

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications RECAL ® - Calcium carbonate

RECAL ® is useful in the prevention and treatment of calcium deficiency states and associated diseases.

Action mechanism RECAL ® - Calcium carbonate

RECAL ® is a calcium carbonate based drug, useful in re-establishing the correct blood concentrations of this element.

Calcium carbonate in fact, introduced by mouth, rapidly reaches the gastric environment where it is transformed into calcium chloride, then absorbed by the intestinal mucosa through both active transport and diffusion processes and facilitated transport.

In this way the calcium taken from the enterocyte is appropriately sorted through the circulatory stream to the various tissues where it mainly intervenes in the control of cellular metabolic activities, in the control of bone turnover and in neuromuscular transmission.

Excess calcium will be eliminated through feces, urine and sweat.

The entire process, from intestinal absorption to peripheral utilization is finely regulated by hormonal factors such as the paratoromone, calcitonin and vitamin D and by the lifestyle of the individual.

Studies carried out and clinical efficacy

1. SOCCER AND PRE-EXTRA SYNDROME

The use of calcium has proved important in reducing fatigue, changes in appetite and depression that is frequently observed in women with premenstrual syndrome.

2. CALCIUM CARBONATE AND OSTEOPOROSIS

The use of calcium carbonate in chewable tablets, has proved more effective than other forms, in reducing blood concentrations of cathepsin K, an important haematic marker of osteoporotic pathology.

3. SOCCER AND CARDIOVASCULAR HEALTH

Study that belies the toxic potential of calcium on cardiovascular health. In fact, in this study supplementation with 1200 mg of calcium per day did not cause any change in the health of the main arteries.

Method of use and dosage

RECAL ®

Calcium carbonate effervescent tablets of 2500 mg equal to 1000 mg of calcium:

the pologic pattern generally used in the treatment of deficiency states, involves the intake of 1 gr of calcium per day.

Dosage changes could be made by your doctor based on the needs of each individual.

The entire therapy must be supervised by your doctor.

RECAL ® warnings - Calcium carbonate

RECAL ® should be preceded by a medical examination to assess the patient's overall health, and in particular the correct kidney function.

Patients with impaired function of this organ are in fact more prone to the risk of hypercalcaemia.

Proper patient management should also include periodic monitoring of calcemia in order to ascertain the therapeutic efficacy.

PREGNANCY AND BREASTFEEDING

Both pregnancy and lactation determine an increased need for calcium, which must necessarily be satisfied through a correct diet or with the help of dedicated supplements.

In the case in which pregnant women and nurses present significant deficiencies of this element, the use of RECAL ® , under prescription and medical supervision, can be valuable in restoring the correct blood calcium concentrations.

Interactions

In order to maintain the pharmacokinetic characteristics of the calcium carbonate taken orally, it is appropriate to pay attention to the simultaneous intake of vitamin D and analogues.

On the contrary, calcium could reduce the bioavailability of antibiotics such as tetracyclines when taken simultaneously or in the following 3 hours.

It is also worth remembering that taking digital could increase the risk of heart rhythm disorders.

Contraindications RECAL ® - Calcium carbonate

RECAL ® intake is contraindicated in cases of hypercalcaemia, hypercalciuria, nephrolithiasis, renal insufficiency and hypersensitivity to the active substance or to one of its excipients.

Undesirable effects - Side effects

Despite the treatment with calcium carbonate, it results to be safe and free from clinically relevant side effects when performed according to medical indications, excessive dosages and protracted for a long time could facilitate the appearance of hypercalcaemia with consequent vomiting, constipation, cramping abdominal pains, polyuria, polydipsia, vasomotor disorders and heart rhythm associated with hypercalcemia.