IRIDINA LIGHT ® is a drug based on Benzalkonium chloride
THERAPEUTIC GROUP: Antiseptics and disinfectants
IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects
Indications IRIDINA LIGHT ® Benzalkonium chloride
IRIDINA LIGHT ® is indicated for cleaning and disinfecting the ocular mucosa.
Action mechanism IRIDINA LIGHT ® Benzalkonium chloride
IRIDINA LIGHT ® is an eyewash based on Benzalkonium chloride, quaternary ammonium salt known for its antiseptic and disinfectant properties.
Used topically, this active ingredient is able to interact with the membranes of bacterial cells, altering their normal structure and causing the formation of pores that inevitably allow nutrients, enzymes and coenzymes to pass through to the point of greatly limiting the biosynthetic capabilities of the pathogen .
This activity, effective against Gram-positive, Gram-negative bacteria and some fungi, guarantees an excellent disinfectant activity, however limited by the poor sensitivity of spores towards Benzalkonium chloride.
Studies carried out and clinical efficacy
HYALURONIC ACID AND BENZALCONIUM CHLORIDE
Mol Vis. 2011; 17: 3364-70. Epub 2011 Dec 21.
Yet another study that demonstrates how the addition of hyaluronic acid to Benzirconio chloride based eye drops can reduce the side effects of this active ingredient and in particular the genotoxic and pro-apoptotic effect.
BENZALCONIUM CHLORIDE AND EXCIPIENTS
J Oleo Sci. 2013; 62 (3): 159-66.
Work that shows how the addition of excipients such as sericin can reduce the toxicity of Benzalkonium chloride, thus enhancing the therapeutic effects of the active ingredient, limiting the collateral ones.
BENZALCONIUM CHLORIDE AND EYE TOXICITY
Invest Ophthalmol Vis Sci. 2013 May 9; 54 (5): 3385-93. doi: 10.1167 / iovs.12-11181.
Experimental study which demonstrates the toxicity of benzalkonium chloride at high doses on the ocular mucosa, identifies potential excipients such as sodium hyaluronate capable of reducing the potential side effects of the disinfectant.
Method of use and dosage
IRIDINA LIGHT ®
Eye drops of 0.1 mg per ml of solution.
Generally it is recommended to apply one or two drops per eye up to 5-6 times a day.
Warnings IRIDINA LIGHT ® Benzalkonium chloride
The use of IRIDINA LIGHT ® should be limited to short-term therapies, note the ability of the active principle to irritate the eye structures with sometimes serious consequences following the continuous application of the product, especially on inflamed or abraded mucous membranes.
It is recommended to avoid ingestion or inhalation of the product, remembering to keep the drug out of the reach of children.
IRIDINA LIGHT ® should not be used while wearing contact lenses, remembering to wait at least 15 minutes after instilling the drug before applying the lenses.
PREGNANCY AND BREASTFEEDING
IRIDINA LIGHT ® can be used during pregnancy and in the subsequent breastfeeding period, always under the supervision of your doctor.
Interactions
It is recommended to avoid the simultaneous use of other antiseptics or detergents.
Contraindications IRIDINA LIGHT ® Benzalkonium chloride
The use of IRIDINA LIGHT ® is contraindicated in patients who are hypersensitive to the active ingredient or to one of its excipients.
Undesirable effects - Side effects
The use of IRIDINA LIGHT ® could sometimes lead to the appearance of local adverse reactions such as burning or irritation.
Prolonged use over time, on the other hand, could cause clinically relevant side effects to damage the ocular mucosa.
Note
IRIDINA LIGHT ® is a drug not subject to mandatory medical prescription.
