Category autoimmune diseases

What is the LES? The term lupus was historically used for the first time to indicate a lesion to the face that, with a certain imagination, was considered similar to that caused by the bite of a wolf. LES ( Systemic Lupus Erythematosus ) is a systemic inflammatory disease, ie spread to the whole body, which manifests itself with extremely varied clinical pictures

Course and evolution With the use of appropriate therapy, the average survival of Systemic Lupus Erythematosus patients is currently around 8-10 years from the time of diagnosis. In some cases the course is benign, especially when vital organs are spared, in other cases it is very serious. It is often characterized by exacerbations and remission of symptoms

Systemic Lupus Erythematosus usually occurs between the ages of 20 and 40, but has been described at all ages. The subject most frequently affected is a woman of childbearing age. General symptoms General symptoms include: temperature, asthenia (weakness), weight loss, anorexia, general malaise. Fever can be of different types: more often it is very high, or it can be moderate, or even a low-grade fever

Generality Sjögren's syndrome is an inflammatory disease caused by an anomaly of the immune system. The characteristic symptoms of this autoimmune disease arise at the level of the exocrine glands, in particular those of the eye and the oral cavity; subsequently, other organs and tissues of the organism are also involved.

Diagnosis As seen in the introductory article, the symptoms of Sjögren's syndrome are numerous and affect more organs and tissues. Therefore, the diagnosis of the syndrome is based on several investigations. The main ones are: Ophthalmological tests Blood tests Labial biopsy Scintigraphy and sialography Scialometria OPHTHALMOLOGICAL TESTS In Sjögren's syndrome, they play a leading role.

Generality Autoimmune diseases are particular pathologies that arise following a malfunction of the immune system. In an individual with an autoimmune disease, in fact, the cells and glycoproteins, which make up the immune system, attack the organism which they should instead defend against pathogens and other threats present in the external environment

Generality Myasthenia gravis is a chronic condition characterized by fatigue and weakness of some muscles. It is an autoimmune disease in which the normal transmission of contractile signals, sent from the nerve to the muscle, is compromised. The alteration of these stimuli results in fluctuating levels of weakness and fatigue, which arise quickly and become worse following the use of certain groups of muscles; not surprisingly, the name "myasthenia gravis" means severe ( gravis ) weakness ( asthenia ) muscle ( myo )

Related articles: Cryoglobulinemia Definition Cryoglobulinemia is a pathological condition characterized by the presence in the plasma of cryoglobulins, ie proteins able to form reversible immunocomplexes and to precipitate at low temperatures, and then solubilize again at 37 ° C. This cryoprecipitate can be formed, specifically, by immunoglobulins IgG, IgA or IgM, present in a monoclonal or mixed form, whose production derives from a chronic stimulation of the immune system, as occurs during autoimmune, inflammatory and infectious diseases.

Related articles: Systemic lupus erythematosus Definition Systemic lupus erythematosus (SLE) is a chronic, multisystem inflammatory disease of autoimmune origin; it means that the immune defenses, normally directed against external agents, attack the body triggering a generalized inflammatory process