TINSET (gel) ® Oxatomide

TINSET ® is a drug based on Oxatomid

THERAPEUTIC GROUP: Antipruriginosi including antihistamines, anesthetics, etc.

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications TINSET (gel) ® Oxatomide

TINSET ® gel is indicated for the treatment of itchy dermatitis, insect bites and sunburn.

Mechanism of action TINSET (gel) ® Oxatomide

TINSET ® is a drug based on Oxatomide, an antihistamine used clinically both systemically and topically.

Topical use, limiting the systemic absorption of the active ingredient, ensures a significant reduction in the incidence of potential side effects, thus making the therapy effective and safe.

The Oxatomide by inhibiting the action of histamine on H1 receptors, serotonin and leukotrienes determines:

the reduction of capillary permeability;
edema typical of inflammatory and allergic manifestations;
control of itching and pain;
the reduction of the typical signs of inflammation.

All the aforementioned activities determine a clear improvement in the symptomatology that is observed in the course of minor pathologies determined by a hypersecretion of histamine.

Studies carried out and clinical efficacy

SIDE EFFECTS OF OXATOMIDE

Ital J Pediatr. 2012 Mar 30; 38 (1): 11. doi: 10.1186 / 1824-7288-38-11.

Case report that denounces the appearance of unpleasant side effects and in particular the loss of consciousness in patients treated at therapeutic doses with Oxatomide, reaffirming the importance of carefully evaluating all the potential contraindications to the use of this drug.

OXATOMIDE IN MUSCULAR DYSTROPHY

Eur J Paediatr Neurol. 2007 Nov; 11 (6): 337-40. Epub 2007 Apr 24.

Pilot study that evaluates the efficacy of oxatomide in the treatment of Duchenne muscular dystrophy in young patients aged 5 to 10 years. Unfortunately the results obtained are not particularly encouraging.

OXATOMIDE IN THE TREATMENT OF MEDIUM THUMB

Laryngoscope. 2006 Sep; 116 (9): 1642-6.

Work demonstrating the efficacy of the oxatomide and soluble TNF receptor in suppressing the symptomatology present in the course of immune mediated otitis media.

Method of use and dosage

TINSET ®

Gel for cutaneous use at 5% of Oxatomide hydrate.

Depending on the degree of inflammation and the severity of the complained symptomatology, it is recommended to apply the appropriate quantity of cream directly on the region affected by the pathological process, 2-3 times a day, taking care to gently massage the area in order to guarantee the best absorption of the drug.

Warnings TINSET (gel) ® Oxatomide

The use of TINSET ® should be preceded by an appropriate medical examination in order to clarify the origin of the symptomatology and the consequent prescriptive appropriateness.

The use of antihistamines for topical use, especially when prolonged over time, could lead to the appearance of unpleasant side effects, fortunately of a local and transitory nature.

Consequently, in order to limit the onset of such reactions and at the same time optimize the therapeutic efficacy, the patient should respect certain health and hygiene rules such as: cleanse the hands after each application, carefully follow the prescriptions of your doctor, avoid contact of the drug with eyes and mucous membranes, avoid application of the drug on secreting wounds and on particularly large skin areas and avoid exposure of the treated region to ultraviolet radiation.

It is advisable to keep the medicine out of the reach of children.

PREGNANCY AND BREASTFEEDING

The use of TINSET ® during pregnancy and in the subsequent period of breastfeeding could be realized only in cases of real need and always under strict medical supervision.

Interactions

Drug interactions worthy of clinical note are currently unknown.

Contraindications TINSET (gel) ® Oxatomide

The use of TINSET ® is contraindicated in patients who are hypersensitive to the active substance or to one of its excipients.

Undesirable effects - Side effects

The use of TINSET ® in gel is generally safe and well tolerated.

The most frequently observed adverse reactions such as redness, erythema and burning are generally local and transient and of little clinical relevance.