FUCIDIN ® Fusidic Acid

FUCIDIN ® is a drug based on Fusidic Acid

THERAPEUTIC GROUP: Chemotherapy for topical use

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications FUCIDIN ® Fusidico Acid

FUCIDIN ® is indicated in the treatment of infections caused by bacteria sensitive to fusidic acid.

Mechanism of action FUCIDIN ® Fusidic Acid

FUCIDIN ® is a medicinal specialty based on Fusidic Acid, a natural antibiotic extracted from Fusidium Coccineum, from which the name derives, which is effective against Gram positive organisms such as Staphylococcus aureus, Propionibacterium acnes and Corynebacteria.

Applied topically, this antibiotic is able to easily permeate the plasma membranes of the bacteria, binding and inhibiting a factor, known as the G elation factor, involved in the synthesis of the peptide chain.

Evidently this inhibition induces a block of protein synthesis with a consequent lack of enzymatic factors and structural proteins that determine the death of the microorganism.

Following the topical application of FUCIDIN ® Fusidic acid is not absorbed systemically, thus reducing the risk of potential side effects.

Studies carried out and clinical efficacy

FUSIDIC ACID IN THE ECZEMA SEVERO

J Drugs Dermatol. 2012 Jul; 11 (7): 861-4.

Interesting study that demonstrates the effectiveness of the combination of fusidic acid and topical corticosteroids in controlling the symptoms associated with S.Aureus infections and improving the clinical appearance of severe eczema.

FUSIDIC ACID AND CIRCUMFACIAL PLASMACYTOSIS

J Dermatol. 2009 Apr; 36 (4): 232-6. doi: 10.1111 / j.1346-8138.2009.00629.x.

Interesting work that demonstrates for the first time the efficacy of fusidic acid in the treatment of circumfacial plasmacytosis, with a clear improvement in both the symptoms and the histological conditions of the tissue.

THE EFFECTIVENESS OF FUSID ACID IN STAPHILOCOCCUS INFECTIONS RESISTANT METICILLINE

Burns. 2005 Nov; 31 (7): 874-7. Epub 2005 Jul 11.

Experimental study that demonstrates the greater efficacy of fusidic acid than other antibiotics in the treatment of cutaneous infections sustained by methicillin-resistant Staphylococcus especially in the case of burns.

Method of use and dosage

FUCIDIN ®

Cream and ointment for cutaneous use of 20 mg of fusidic acid.

Always according to medical indications, 2-3 applications per day are generally recommended, depending on the severity of the infection and the patient's clinical conditions.

Warnings FUCIDIN ® Fusidic Acid

Although the side effects of topically applied fusidic acid are not very relevant from a clinical point of view, it should be remembered that the correct use of this medicine provides for an adequate medical consultation.

Prolonged use of FUCIDIN ® could lead to the onset of local adverse reactions, the appearance of which should prompt the patient to consult their doctor immediately, taking into consideration the possibility of suspending the therapy in progress.

At the same time, the patient should respect a series of sanitary regulations useful for optimizing the therapeutic efficacy of the drug, limiting its potential side effects.

The presence of particular excipients, endowed with allergenic power, could induce adverse local reactions.

It is advisable to keep the medicine out of the reach of children.

PREGNANCY AND BREASTFEEDING

The use of FUCIDIN ® during pregnancy and in the subsequent period of breastfeeding should be limited to cases of real need and always take place under the strict supervision of your doctor.