OPTREX ® Distilled water of Hamamelis Virginiana

OPTREX ® is a distilled water based drug of Hamamelis Virginiana.

THERAPEUTIC GROUP: Other ophthalmologicals

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications OPTREX ® Distilled water of Hamamelis Virginiana

OPTREX ® is indicated as a lubricant, decongestant and ocular antiseptic.

Mechanism of action OPTREX ® Distilled water of Hamamelis Virginiana

OPTREX ® is a drug obtained from the Hamamelis Virginiana, more commonly known as Witch Hazel, a large-sized plant whose leaves and bark can extract phytotherapeutic complexes rich in tannins and therefore equipped with:

decongestant properties, important in avoiding edema and swelling associated with phlogistic events;
astringent;
healing;
hemostats.

Following the ocular application the aforementioned properties have proved to be clinically important in cases of redness and ocular congestion, excessive tearing or irritation of the conjunctiva, eyelid and tear ducts.

Studies carried out and clinical efficacy

HAMAMELIS AND UV-RHYTHYMA

Skin Pharmacol Appl Skin Physiol. 2002 Mar-Apr; 15 (2): 125-32.

An interesting study that demonstrates how Hamamelis-based solutions can be effective in reducing the erythematous inflammatory event of the skin associated with massive exposure to UV rays.

HAMAMELIS AND SKIN DISTURBANCES IN SMALL PATIENTS

Eur J Pediatr. 2007 Sep; 166 (9): 943-8. Epub 2006 Dec 20.

Clinical trial conducted on over 300 patients demonstrating how Hamamelis can be effective in the treatment of simple skin disorders in small patients up to 11 years of age.

HAMAMELIS AND CYTOTOXIC ACTIVITY IN VITRO

J Nat Prod. 2012 Jan 27; 75 (1): 26-33. doi: 10.1021 / np200426k. Epub 2012 Jan 4.

Experimental study demonstrating that tannins extracted from Hamamelis Virginiana may have a specific cytotoxic activity against colon cancer cells.

Method of use and dosage

Eye bath and eye drops at 13% distilled water of Hamamelis Virginiana

It is generally recommended to apply 2-3 drops of eye drops per eye 2-3 times a day or 1-3 applications of ocular bath fluid 2-3 times a day.

Warnings OPTREX ® Hamamelis Virginiana distilled water

Although the use of OPTREX ® appears to be generally safe and free of side effects, it would be preferable to consult the doctor before starting the use of this drug in order to ascertain the pathogenic events determining the conditions of eye irritation.

If the treatment does not have positive effects in 7 days, it would be preferable to suspend it and consult your doctor.

As eye drops it is recommended to pay close attention to the methods of use, considering that its ingestion with the consequent systemic absorption could cause serious side effects.

In any case, extreme caution should be exercised in patients suffering from hypertension, heart disease and thyroid pathologies and at the same time undergoing therapy with OPTREX ®.

It is recommended to avoid the use of contact lenses together with the administration of OPTREX ®.

PREGNANCY AND BREASTFEEDING

OPTREX ® can be used during pregnancy and lactation, always under strict medical supervision.

Interactions

Although no clinically relevant drug interactions are currently known, the simultaneous application of eye drops or ophthalmic preparations should be avoided.

Contraindications OPTREX ® Distilled water of Hamamelis Virginiana

The use of OPTREX ® is contraindicated in patients who are hypersensitive to the active substance or to one of its excipients and in patients with glaucoma or ocular vascular diseases.

Undesirable effects - Side effects

The use of OPTREX ®, especially in sensitive subjects or following prolonged use, could determine the appearance of local side effects such as redness and burning.

Given the absence of systemic absorption, clinically important adverse reactions are decidedly rarer.