infectious diseases

Exanthematic diseases

Generality

Exanthematous diseases are all those infectious diseases, both viral and bacterial in nature, which cause a typical rash accompanied by a series of other symptoms, such as: fever, malaise, lack of appetite, headache, abdominal pain, irritability and muscle pain.

The exanthematic diseases par excellence are: measles, rubella, scarlet fever, varicella, the fourth disease, the fifth disease and the sixth disease. These morbid conditions are particularly common in the young and very young population.

Physical examination and medical history (or medical history) are often sufficient to diagnose exanthematous diseases.

The treatment depends on the type of exanthematous disease in progress: the most common viral exanthematous diseases provide, for the most part, a symptomatic therapy; exanthematous diseases of bacterial origin, on the other hand, provide a therapy based on antibiotics, to fight bacteria that infect the organism.

What are exanthematous diseases?

The exanthematous diseases are those morbid conditions, of infectious origin, usually viral, which cause a typical rash (called exanthema or rash ); this "rash" is accompanied by a series of other manifestations, such as fever, malaise and loss of appetite.

MAIN EXANTEMATIC DISEASES

The exanthematic diseases par excellence are:

  • Measles
  • Rubella
  • Chickenpox
  • Scarlet fever
  • The fourth illness
  • The fifth disease
  • The sixth disease

These conditions are very common and known.

LESS KNOWN EXAMINATION DISEASES

Less common and / or known than the previous ones, but still exanthematic diseases are:

  • Typhus
  • Syphilis
  • AIDS or HIV
  • The disease "hands feet mouth"
  • Smallpox
  • Viral hepatitis
  • Infectious mononucleosis
  • Papular acrodermatitis or Gianotti-Crosti syndrome
  • Erythema multiforme
  • The papulo-purpurica syndrome "gloves and socks"
  • The generalized acute exanthematous pustulosis
  • Pityriasis rosea
  • Toxic shock syndrome
  • Pseudo-burn skin syndrome or staphylococcal skin syndrome
  • Kawasaki syndrome
  • Mycoplasma pneumonia or atypical pneumonia
  • The rickettsiosi

Epidemiology

Exanthematous diseases par excellence are morbid conditions that usually affect individuals of young or very young age .

The particular predisposition of very young subjects to contract the most common exanthematous diseases is linked, essentially, to two factors: the immune system not yet fully developed and efficient, and the high contagiousness of the infectious agents, which increases the risk of infection for those who live in communities such as schools or kindergartens.

ORIGIN OF THE TERM EXANTEME AND DERIVATIVES

The term exanthem derives from the Greek word " exanthema " ( ἐξάνθημα ), which means "burst", but also "vent".

A rash is a vent on the skin, very similar to a volcanic eruption (hence the use of the term "rash" to define a rash).

Causes

The cause of many exanthematous diseases is viral, which is a virus that determines the morbid condition.

However, it is worth remembering that there are exanthematic diseases due to bacteria and exanthematous diseases whose infectious agents are, at the moment, unknown (they could be viruses, bacteria or other).

Exanthematic diseases and causes
Viral originDiseaseInfectious agent
chickenpoxVaricella-zoster virus
Measlesmorbillivirus
RubellaRubella virus
Fifth diseaseParvovirus B19
Sixth diseaseHerpes virus B6
AIDSHIV or human immunodeficiency virus
Viral hepatitisHepatovirus
Infectious mononucleosisEpstein Barr virus
Illness hands feet mouthCoxsackie virus
Bacterial originFourth diseaseType A beta-hemolytic streptococcus (probably)
Scarlet feverType A beta-hemolytic streptococcus
Toxic shock syndromeStaphylococcus aureus ( Staphylococcus aureus )
Pseudo-burned skin syndromeStaphylococcus aureus ( Staphylococcus aureus )
Mycoplasma pneumoniaMycoplasma pneumoniae

Symptoms and Complications

The rash that accompanies exanthematous diseases can occur in various ways: with patches of different sizes, with small spots, with skin redness (erythema), with itching, with blisters and / or with papules.

The characteristics of the rash depend on the triggering agent, therefore on the type of exanthematic disease.

To investigate the characteristics of the rash of the most common exanthematous diseases:

  • Measles
  • Rubella
  • Scarlet fever
  • chickenpox

ASSOCIATED MANIFESTATIONS

As stated in the definition of exanthematous diseases, the presence of these morbid conditions includes, in addition to the exanthema, also a series of other manifestations or disorders.

The manifestations associated with the rash include:

  • Temperature
  • malaise
  • Headache
  • Loss of appetite
  • Abdominal pain
  • Irritability
  • Soreness or real muscle pain

Similarly to the rash, the aforementioned symptoms and signs also depend on the type of exanthematous disease in progress.

MORE AFFECTED OFFICES

The rash that characterizes exanthematous diseases can affect any part of the human body.

However, it is good to point out that there are more affected anatomical areas than others, such as: the face, the trunk (ie chest, belly and back) and the extremities (ie hands and feet).

A USEFUL CLASSIFICATION

Doctors have decided to classify some exanthematous diseases based on where the rash usually begins.

This way of proceeding led to the following scheme:

  • Exanthematic diseases whose rash tends to begin with the face :
    • Measles
    • Rubella
    • Fifth disease
    • Scarlet fever
  • Exanthematic diseases whose rash tends to begin with the trunk :
    • chickenpox
    • Sixth disease
  • Exanthematic diseases whose rash tends to begin at the extremities :
    • Papulo-purpurica syndrome "gloves and socks"
    • Illness hands feet mouth

The failure to include various exanthematous diseases in this scheme is due to the fact that these tend to begin, without distinction, in the trunk, in the face and / or in the extremities of the limbs.

COMPLICATIONS

Exanthematous diseases can involve various complications, some of which are also particularly serious and with permanent results.

For example, measles can cause otitis media, pneumonia, diarrhea and convulsions more often than not; very rarely, it can give rise to severe and sometimes lethal encephalitis (1 case of measles every 5, 000 is lethal due to encephalitis).

Rubella is an usually not very aggressive infection, which however can represent a serious danger for adults, especially for pregnant women. Like measles, rubella can also induce encephalitis.

Scarlet fever can cause ear infections, throat abscesses, sinusitis, pneumonia, meningitis, bone or joint problems, liver damage, kidney damage and rheumatic fever with associated heart problems (NB: complications from bone problems onwards they are very rare).

To investigate the issue of complications related to exanthematous diseases, readers can consult the articles present here (fourth illness), here (fifth illness) and here (sixth illness).

Diagnosis

In general, to diagnose exanthematous diseases, doctors only use physical examination and medical history (or clinical history), as observation and evaluation of the symptom picture are often rich in fundamental information.

Examination of saliva (using a swab) and blood tests takes place only in case of doubt.

Treatment

For the most common viral exanthematous diseases, treatment is generally symptomatic .

The doctors define the treatments aimed at improving the symptomatic situation symptomatic, therefore the therapies that aim to alleviate the manifestations of the disease in progress.

Returning therefore to the most common exanthematous viral diseases, the symptomatic remedies for this type of conditions consist in: rest, intake of paracetamol (to lower fever), application of emollients to the skin (to soothe some symptoms of the rash) and antihistamines ( to cope with intense itching).

For exanthematous bacterial diseases, such as scarlet fever, the situation is slightly different and the treatment is causal, ie aimed at treating the causes.

In these situations, therefore, the therapy consists of antibiotic drugs, whose purpose is to eliminate the bacterial colonies infesting the organism.

To know more:

  • Measles treatment medications
  • Medicines for the treatment of rubella
  • Varicella medications
  • Scarlet fever medications
  • Drugs for the treatment of the sixth disease

SPECIAL CASES

Severe exanthematic diseases and / or frequent unpleasant consequences, such as AIDS or typhoid, require targeted treatments and the observance of important precautions, to avoid the contagion of other people.

For the most serious viral exanthematous diseases, the therapy involves the administration of antiviral drugs .

Prevention

Today, various exanthematous diseases are preventable through specific vaccines .

Among the exanthematic diseases par excellence, those for which an effective vaccination exists are: measles, rubella and chickenpox.

Prognosis

The prognosis of exanthematous diseases varies according to the severity of the ongoing exanthematous disease.

Exanthematous diseases par excellence generally have a positive prognosis. Nevertheless, doctors recommend, whenever possible, to provide for appropriate vaccinations anyway.

Exanthematic diseases, such as AIDS or smallpox, have, notoriously, a fatal outcome.