DUOFILM ® Salicylic acid and lactic acid

DUOFILM ® is a drug with salicylic acid and lactic acid

THERAPEUTIC GROUP: Other dermatological preparations

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications DUOFILM ® Salicylic acid and lactic acid

DUOFILM ® is indicated for the topical treatment of warts and hyperkeratosis

Mechanism of action DUOFILM ® Salicylic acid and lactic acid

DUOFILM ® owes its therapeutic properties to the presence of its two active ingredients: lactic acid and salicylic acid.

Both characterized by important keratolytic properties, applied topically, as they are highly irritating to the gastric mucosa, guarantee a normalization of the cutaneous tissue reducing the classical hyperkeratosis present during corns and warts and restoring the correct balance of the stratum corneum.

The aforementioned activities are also aided by the fungicidal action of salicylic acid, which is important in reducing the harmful action of fungi and pathogenic microorganisms that usually contribute to the pathogenesis of these manifestations.

Studies carried out and clinical efficacy

EFFECTIVENESS AND SAFETY OF LACTIC AND SALICYLIC ACID IN THE TREATMENT OF WARTS

Mymensingh Med J. 2012 Oct; 2: 145-53.

Interesting study that shows how the distribution of salicylic acid in the stratum corneum does not depend so much on the dosage used as on the pharmaceutical formulation. In particular, the topical bioavailability of the product appears to be maximum in colloid formulations.

PLANTAR WARS IN HIV POSITIVE PATIENTS: THE IMPORTANCE OF PREVENTION

J Am Podiatr Med Assoc. 2001 Feb; 91 (2): 79-84.

Study demonstrating the need to devise a prevention protocol and not just a therapeutic one for the treatment of plantar warts in HIV positive patients, and therefore decidedly more subject to these cutaneous manifestations.

Method of use and dosage

DUOFILM ®

Collodi 16.7% salicylic acid and 16.7% lactic acid.

Generally we recommend the application of the drug, using the supplied brush, in the appropriate quantities only on the skin region to be treated, taking care to avoid contact with the intact areas once a day, preferably in the evening.

Warnings DUOFILM ® Salicylic acid and lactic acid

Given the strong keratolytic power of the active ingredients present in DUOFILM ®, it is recommended to avoid contact of the drug with healthy skin regions, with mucous membranes and eyes, taking care to rinse hands thoroughly after each application, in order to remove any excesses of drug.

It is recommended to keep the drug out of the reach of children considering also how prolonged use could significantly increase the risk of adverse reactions.

PREGNANCY AND BREASTFEEDING

It would be preferable to limit the use of DUOFILM ® during pregnancy and lactation exclusively to cases of real need and always under the strict supervision of your doctor.

Interactions

Pharmacological interactions worthy of note are not currently known, however it is recommended to avoid the simultaneous use of other keratolytic products.

Contraindications DUOFILM ® Salicylic acid and lactic acid

The use of DUOFILM ® is contraindicated in patients hypersensitive to the active ingredient or to one of its excipients and in diabetic and cardiopathic patients.

It is also recommended to avoid the application of the drug on the face, on the anogenital area, on the nerves and in the case of seborrheic warts, condyloma and facial warts.