Protein Silver

THERAPEUTIC GROUP: Nasal decongestants and other preparations for topical use

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Directions Silver Protein

Silver Protein is used as an ear antiseptic, an antiseptic for topical use and a nasal decongestant

Mechanism of action Silver Protein

Silver proteinate, often called vitelline silver, is an active ingredient consisting of organic molecules and silver ions successfully used in clinical settings both as an antiseptic and as a decongestant of the nasal mucosa.

The mostly bacteriostatic effect is determined by the ability of this molecule to inhibit bacterial replication by exerting a seen pro-oxidant effect, such as to alter the normal metabolic capacities of the micro-organism inducing at first the block of replication processes and subsequently death.

The decongestant effect, on the other hand, has not yet been fully clarified, although it is assumed the ability to determine a precipitation of serum exudate proteins, resulting in a better compartmentalization of the water state and a reduction of the associated edema.

Everything is facilitated by the good pharmacokinetic properties of the silver proteinate, which limit the systemic absorption of the ion and the potential side effects.

Studies carried out and clinical efficacy

BIBLIOGRAPHICAL CONSIDERATIONS

All studies relating to the efficacy of colloidal silver in the clinical setting are particularly dated, demonstrating the common use made of this active ingredient in clinical practice.

Despite this, recent scientific evidences, some of which are published below, demonstrate the potential new uses of Silver in medicine, debunking some myths and opening therapeutic perspectives of particular clinical interest.

SILVER IN HEALING THE WOUNDS

Med Hypotheses. 2012 Oct; 79 (4): 542-3. doi: 10.1016 / j.mehy.2012.07.015. Epub 2012 Aug 3.

Study that tests the silver's potential in wound healing, and in particular anoretal fistulas, thus potentially saving surgical therapy, which is decidedly more invasive and with greater complications.

SILVER IN HOMEOPATHY

Complement Ther Med. 2003 Jun; 11 (2): 65-71.

Study that emphasizes the futility of homeopathic silver in the treatment of generalized anxiety disorder in the university student population.

Method of use and dosage

The silver protein is found in ear drops or in drops by nasal instillation concentrated at 0.5% - 1% and 2%.

According to medical indications it is generally recommended to instill 1 or 2 drops directly into the ear canal several times a day, and 1-3 drops per nostril several times a day.

Warnings Silver Protein

Prolonged use of silver proteinate could cause the appearance of hypersensitivity reactions to the active principle which would require suspension of the therapy in progress.

It is also advisable to keep the drug out of the reach of children, to avoid inappropriate use and potentially very dangerous ingestion.

PREGNANCY AND BREASTFEEDING

The use of silver proteinate during pregnancy and lactation should be limited to cases of real need and evidently supervised by one's gynecologist.

Interactions

Drug interactions worthy of clinical note are currently unknown.

Contraindications Silver Protein

The use of Silver Protein is contraindicated in patients who are hypersensitive to the active ingredient or to structurally related drugs.

Undesirable effects - Side effects

The use of silver proteinate, especially if continued for a long time, could determine the onset of local adverse reactions such as burning, redness and pain.