drugs

Candida Vulvovaginitis drugs

Definition

Candida vulvovaginitis is a symptomatic inflammation of the vulva and vagina, caused by fungi belonging to the genus Candida: it is a pathology as annoying as it is common, responsible for most of the female genital infections. Unfortunately, candida vulvovaginitis tends to recur.

Causes

Multiple causes responsible for vulvovaginal candidiasis: Candida is a commensal fungus but, under certain conditions, it turns into opportunistic, creating damage. Vulvovaginal infection is favored by: IV drug abuse, AIDS, urinary catheter, endocrine dysfunction, leukemia, autoimmune disorders, trauma, tumors.

Among the predisposing factors recurrent candida vulvovaginitis are: antibiotics, intake of estrogen progestins, diabetes mellitus and pregnancy.

Symptoms

Candida vulvovaginitis generally begins with itching accompanied by burning, constant discomfort, pain during intercourse (dyspareunia) and irritation, and then degenerates into pain at urination, unbearable itching, whitish leaks similar to ricotta, sometimes smelly.

Natural Care

Diet and Nutrition

Information on Candida Vulvovaginitis Drugs is not intended to replace the direct relationship between health professional and patient. Always consult your doctor and / or specialist before taking Medications to Treat Candida Vulvovaginitis.

drugs

As with thrush and candidiasis in general, candida vulvovaginitis can also be cured with azole, polyene and echinocandin drugs: therapy can be topical and / or systemic.

Candida vulvovaginitis is one of the sexually transmitted diseases, therefore even the partner can be infected and constitute a possible source of reinfection: in this regard, it is good to also subject the partner to a targeted cure, even in the absence of symptoms.

AZOLIC DRUGS

  • Fluconazole (eg Diflucan): the recommended dose for Candida vulvovaginitis is 150 mg (tablets), taken in a single dose. For relapsing forms, oral administration in a single dose (100 mg) is recommended once a week for at least six months.
  • Clotrimazole (eg. Gyne-Lotrimin, Gyne-Lotrimin-3, Mycelex-7 and, subject to medical prescription, Gyno-canesten): insert a vaginal tablet (100 mg) deeply into the vagina - or apply the cream using a special applicator (1% ) - for 7 consecutive days, before going to bed. For recurrent candida vulvovaginitis, we recommend applying a 500 mg clotrimazole (vaginal) glow plug once a week for six months.
  • Itraconazole (eg Sporanox): is an azole drug that acts as an antifungal, interfering with the formation of the cell membrane of the fungus. Generally, it is given in the form of an oral suspension or tablets (200 mg): one tablet is taken per day for one or two weeks. The dose may increase from 100 to 400 mg a day, depending on what your doctor has prescribed.

F POLYENIC ARMY

This class of drugs is represented by amphotericin B and nystatin: both act as potent antifungals.

  • Amphotericin B (eg Fungilin): taken orally, amphotericin B is given as a slow IV infusion, at a dose of 0.5-1 mg / kg per day from 1 to 7 days. The topical application of creams formulated with Amphotericin B is also used successfully.

Being a parenteral administration, the danger of side effects and toxicity is higher, therefore it is necessary to monitor the patient.

  • Nystatin (eg. Mycostatin, Nizoral) The administration of 500.00 IU tablets of nystatin per ml (or 100, 000 IU / ml oral suspension) three times a day is recommended. The duration of therapy must be established by the doctor.

echinocandins

Echinocandins are recent drugs used in the treatment of generalized candidiasis and candida vulvovaginitis: we are talking about large cyclic peptides linked to a long chain fatty acid. This category includes:

  • Anidulafungina (eg Ecalta) is presented in powder form for infusion solutions. Although more suitable for systemic candidiasis, it is sometimes prescribed even in the case of candida vulvovaginitis. It is given with an initial dose of 200 mg on the first day, followed by 100 mg / day for about two weeks. The duration of the treatment must be established by the doctor.
  • Cancidas (eg Caspofungin): it is administered with a single loading dose of 70 mg, followed by a dose of 50 mg a day (or 70 mg if the subject weighs more than 80 kg). The duration of therapy is indicated by the doctor.
  • Mycamine (eg. Micafungin): it is a fungicidal antibiotic drug, used both in the treatment and in the prophylaxis of Candida infections. For the treatment of esophageal candidiasis, the dosage is 150 mg a day for 15-30 days (for fungal infections) and 50 mg a day for prophylaxis.

NB: taking antibiotics causes a marked alteration of the bacterial flora: in this regard it is advisable to take lactic ferments during therapy and after its suspension, in order to restore the intestinal bacterial flora.

Most drugs used in candida vulvovaginitis therapy require a medical prescription.