BRAUNOL ® Iodopovidone

BRAUNOL ® is a drug based on Iodopovidone

THERAPEUTIC GROUP: Antiseptics and disinfectants

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications BRAUNOL ® Iodopovidone

BRAUNOL ® is used for the cleaning and disinfection of intact and damaged skin as well as the operating field.

Mechanism of action BRAUNOL ® Iodopovidone

BRAUNOL ® is a disinfectant based on Iodopovidone, an iodophora macromolecule capable of complexing the iodine, guaranteeing a gradual release over time, therefore a prolonged antiseptic and disinfectant action both against Gram positive bacteria and Gram negative bacteria and to a small extent also of mushrooms and yeasts.

The aforementioned biological activity is, however, to be correlated to the proportion of free iodine released by polyvinylpyrrolidone, capable of interacting with sulfhydryl residues of enzymes and bacterial proteins, determining structural changes that inevitably compromise their functionality.

All this generally takes place with the control of bacterial proliferation and in certain cases even with the death of the same.

Studies carried out and clinical efficacy

IODOPOVIDONE IN GYNECOLOGICAL CLINIC

Obstet Gynecol. 2012 Nov; 120 (5): 1037-44. doi: //10.1097/AOG.0b013e31826f3bd9.

Interesting work that demonstrates the efficacy at good costs of Iodopovidone in the prevention of surgical infections following cesarean delivery, ensuring a significant reduction in hospitalization times.

CLOREXEDINA VS IODOPOVIDONE

N Engl J Med. 2010 Jan 7; 362 (1): 18-26. doi: 10.1056 / NEJMoa0810988.

Work that evaluates the antiseptic efficacy of Chlorhexidine and Iodopovidone in the prevention of post-operative infections, reaffirming the greater efficacy of Chlorhexidine.

THE IODOPOVIDONE IN THE EYE CLINIC

Eur J Ophthalmol. 2012 Jul-Aug; 22 (4): 541-6. doi: 10.5301 / ejo.5000093.

Interesting work that experiments with iodopovidone in the eye area, demonstrating its effectiveness in preventing bacterial conjunctivitis following cataract surgery.

Method of use and dosage

BRAUNOL ®

7.5% or 10% cutaneous solution of Iodopovidone.

The number of applications to be carried out depends strongly on the extension of the site, generally considering a maximum of 5-6 for small regions, 2-3 for particularly large regions.

The treatment of the surgical field includes different and standardized washing and disinfection procedures.

Warnings BRAUNOL ® Iodopovidone

BRAUNOL ® is indicated exclusively for external use, therefore it would be advisable to exercise extreme caution during its use, avoiding contact with exposed mucous membranes or in severely damaged areas.

The ingestion of BRAUNOL ® could cause the onset of clinically relevant adverse reactions, such as to seriously compromise the patient's state of health.

If the use of this medicine causes the onset of local adverse reactions such as burning or redness, it would be advisable to consult your doctor immediately and consider suspending the therapy in progress.

Remember to store the product in a cool and dry place, away from potential heat sources and out of reach of children.

PREGNANCY AND BREASTFEEDING

The use of BRAUNOL ® is generally contraindicated during pregnancy and in the subsequent period of breastfeeding, especially when used for the dressing of particularly large skin regions.

Should its use prove necessary, medical supervision should be requested.

Interactions

It is recommended to avoid the simultaneous use of other skin or systemic oxidizers and other detergents and antiseptics.

Contraindications BRAUNOL ® Iodopovidone

The use of BRAUNOL ® is contraindicated in patients hypersensitive to the active ingredient or to one of its excipients and in patients with altered thyroid function.