ZINC OXIDE OIL OIL Zinc oxide

ZINCO OSSIDO UNGUENTO ® is a drug based on Zinc oxide.

THERAPEUTIC GROUP: Emollients and protective agents

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Directions ZINC OXIDE OXIDE ® Zinc oxide

ZINCO OSSIDO UNGUENTO ® is used in the treatment of minor skin disorders such as dermatoses and eczema.

Mode of action ZINC OXIDE OIL OIL ® Zinc oxide

Zinc oxide, properly mixed with specific pads and acquired the pharmaceutical form of ointment, can be effectively and easily used in the treatment of minor dermatological diseases such as eczema and dermatoses in general.

Different studies have shown the therapeutic properties of this compound emphasizing the cytoprotective action against ultraviolet, anti-irritative, healing and anti-inflammatory radiation.

Despite the defined therapeutic characteristics, the mechanism of action of zinc oxide has not yet been fully characterized by hypothesizing in addition to the crucial role of cofactor and catalyst also a modulator of gene expression, controlling the expression of genes involved in the inflammation.

Studies carried out and clinical efficacy

MOLECULAR MECHANISMS OF ZINC OXIDE

Nanotoxicology. 2012 Nov; 6 (7): 757-65. doi: 10.3109 / 17435390.2011.620718. Epub 2011 Nov 17.

Molecular work that tries to best characterize the mechanism of action of zinc oxide, highlighting a potential activity represented by the ability to recall and activate cellular elements able to facilitate wound healing.

APOPTOSIS INDUCED BY ZINC OXIDE ON MELANOMA CELL LINES

Int J Nanomedicine. 2013; 8: 983-93. doi: 10.2147 / IJN.S42028. Epub 2013 Mar 6.

A beautiful study that demonstrates how treatment with nano-particles based on zinc oxide can present an important genotoxic action that induces apoptosis in melanoma cell lines.

ACUTE PANCREATITIS FROM INGESTION OF ZINC OXIDE

J Appl Toxicol. 2013 Feb 13. doi: 10.1002 / jat.2862. [Epub ahead of print]

Experimental study demonstrating the potential side effects of ingestion of zinc oxide with the consequent appearance of serious adverse reactions such as acute pancreatitis.

Method of use and dosage

ZINC OXIDE OINTATION ®

Ointment for cutaneous use at 10% of zinc oxide.

It is generally recommended to apply the appropriate amount of ointment locally, one or more times a day depending on the clinical needs.

Warnings ZINC OXID OIL OIL ® Zinc oxide

Zinc oxide should only be used topically, taking care therefore to avoid ingestion or contact with mucous membranes.

If the application of the ointment does not determine appreciable results or rather favors the appearance of adverse reactions such as irritation and redness, it would be advisable to consult your doctor taking into consideration the possibility of suspending the therapy in progress.

It is recommended to keep the medicine in a cool and dry place out of reach of children.

PREGNANCY AND BREASTFEEDING

The use of ZINC OXIDE OXIDO ® during pregnancy and lactation should be justified only in cases of real necessity and should take place under strict medical supervision.

Interactions

No clinically relevant drug interactions are currently known.

Contraindications ZINC OXIDE OXIDE ® Zinc oxide

The use of ZINCO OSSIDO UNGUENTO ® is contraindicated in patients who are hypersensitive to the active ingredient or to one of its excipients and in patients with peripheral circulatory disorders as well as to children under 1 year of age.