What are
Anti-inflammatory plasters are medicated plasters that are applied to intact skin, in order to treat and resolve inflammatory disorders.
Features
How anti-inflammatory patches are made
Anti-inflammatory plasters are usually composed of an acrylic matrix in which the active ingredient is dispersed. This matrix is protected by two strips of silicone paper and is located on a non-woven fabric support (generally of polyester). On the other hand, in the part of the plaster that comes into contact with the skin, there is an adhesive layer protected by a film which, of course, must be removed before applying the patch.
The shape and size of the patches can be different. However, they usually have a rectangular or square shape.
Which active ingredients contain anti-inflammatory patches
Naturally, since they are anti-inflammatory patches, the active ingredients contained in them are able to directly combat inflammation and the typical pain it induces. The active ingredients most commonly used to achieve this are NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Among these, the most commonly used are:
- Ibuprofen (Ibupas®);
- Flurbiprofen (Transact Lat®);
- Ketoprofen (Keplat®);
- Diclofenac (Voltadol®, Flector®);
- Piroxicam (Brexidol®).
Indications
What are anti-inflammatory patches used for
Anti-inflammatory patches are used in the local treatment of painful states induced by inflammatory disorders - both rheumatic and traumatic in nature - of the musculoskeletal system.
Action mechanism
How Anti-inflammatory Patches Work
Once applied, the patch gradually releases the drug dispersed in its matrix. In this way, the active principle is absorbed by the skin and reaches the deeper layers where the inflammatory state that is to be treated is present.
The NSAIDs used inside the anti-inflammatory patches carry out their activity through the inhibition of the cyclooxygenase enzyme. Thanks to this mechanism of action, the consequent inhibition of the synthesis of prostaglandins involved in inflammatory processes and in the mediation of pain responses is obtained.
Use and Posology
How and for how long anti-inflammatory patches are used
Anti-inflammatory patches must be applied to intact, clean and dry skin in the same way that normal patches are applied. Of course, the application must be made at the inflamed and painful area. After application, it is advisable to apply light pressure with the palm of the hand, so that the adhesive layer adheres perfectly to the skin.
Depending on the type of patch used and the active ingredient contained in it, the application time on the skin can be 8, 12 or 24 hours. At the end of the indicated time, the patch can be easily removed, moistening it with a little water, lifting a flap and pulling gently.
Please note
Anti-inflammatory patches should NOT be cut or damaged in any way, as this would cause the active ingredient to leak. Therefore, they must be used intact.
Furthermore, at the end of their application and their removal, it is necessary to wash the hands thoroughly.
Finally, following removal of the patch, exposure to UV rays (solar or artificial) is not recommended, in order to prevent the onset of any photosensitivity reactions.
Side effects
The most common side effects resulting from the use of anti-inflammatory patches mainly concern the site of application of the same patches and are, therefore, local. Among these, we recall:
- Skin irritation;
- Itch;
- Redness;
- Skin exfoliation;
- Dermatitis;
- Burning;
- Dryness of the skin in the area of application of the plaster.
However, depending on the active ingredient used, and depending on its degree of absorption, systemic adverse effects could also occur, such as, for example, a feeling of general malaise, nausea and headache.
However, the type and intensity of the undesirable effects are factors that - in addition to varying depending on the active ingredient used - also vary according to the sensitivity of the patient to the same active ingredient.
Finally, the possible onset of allergic reactions in sensitive individuals should not be forgotten. These reactions can manifest with symptoms such as angioedema, allergic contact dermatitis and / or breathing difficulties.
Contraindications
When anti-inflammatory patches should not be used
The first contraindication to the use of anti-inflammatory patches concerns their application on damaged skin. As stated many times during the article, in fact, these medicines must be used only on intact skin.
Of course, the use of anti-inflammatory patches is contraindicated in patients with known hypersensitivity to the active ingredients contained therein.
Other contraindications concern patients suffering from peptic ulcer disease and children and adolescents under 12-16 years of age (the age limit varies according to the active ingredient present in the patches).
Finally, as a precautionary measure, the use of anti-inflammatory patches in pregnant women and breast-feeding mothers is generally contraindicated, unless otherwise advised by a doctor. In any case, pregnant women and breastfeeding women should seek medical advice before taking any type of medicine.
