CERULISINE ® is a drug based on dimethylbenzene and sweet almond oil
THERAPEUTIC GROUP: Other otologs
IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects
Directions CERULISINA ® Dimethylbenzene and sweet almond oil
CERULISINE ® is indicated in the post-operative medication and cleaning of the middle ear and in the dissolution of ear wax caps.
Mechanism of action CERULISINA ® Dimethylbenzene and sweet almond oil
CERULISINE ® is a drug based on Dimethylbenzene, more commonly known as Xylene, a substance belonging to the group of aromatic hydrocarbons and endowed with marked detergent and solubilizing power.
In fact, immersed in a highly lubricating solution such as sweet almond oil, it allows the detachment and slipping of the cerumen plug together with any other residues present along the entire auditory canal.
In addition to removing any wastes, this activity partially restores the membrane lipid film of the external acoustic meatus, protecting the mucous membrane from possible aggressors.
The aforementioned activities are evidently carried out exclusively by direct contact, thus justifying the application of the drug in ear drops.
Studies carried out and clinical efficacy
POLLUTION BY ORGANIC SOLVENTS
Environ Health. 2012 Jul 31; 11: 51. doi: 10.1186 / 1476-069X-11-51.
Very interesting study that evaluates the exposure of New Yorkers to organic solvents such as Xylene, comparing it to the onset of disorders related from a physiopathological point of view and to the different incidence of diseases in different areas of the city.
ACCIDENTAL EXPOSURE TO XYLENE
J Am Acad Audiol. 2012 Nov-Dec; 23 (10): 824-30. doi: 10.3766 / jaaa.23.10.7.
Work that reports bilateral hearing loss following accidental exposure to Xylene in laboratory workers, thus reaffirming the importance of safety at work.
XILENE POISONING
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013 May; 31 (5): 369-71.
Study that recalls the toxic potential of Xylene, especially after ingestion, which represents one of the most frequent domestic poisonings.
Method of use and dosage
CERULISINA ®
Otological solution of 5 g of Dimethylbenzene and 95 g of sweet almond oil.
Instructions concerning the correct application of CERULISINE ® should be provided by your doctor.
Generally we recommend the instillation of the contents of an eyedropper directly into the external acoustic meatus, with the head tilted for 5-10 minutes, followed by washing the ear with warm water.
Should the cork be particularly resistant, it would be advisable to repeat the application 2-3 times a day for a maximum of 3-5 days.
Warnings CERULISINA ® Dimethylbenzene and sweet almond oil
The use of CERULISINE ® should be limited in time and evidently compared to the possibility of removing the wax plug.
The inappropriate use of this drug or in the presence of lesions of the tympanic membrane, could determine the onset of side effects and sensitization phenomena.
PREGNANCY AND BREASTFEEDING
CERULISINE ® can be used during pregnancy and in the subsequent breastfeeding period, always after consulting your gynecologist.
Interactions
Drug interactions worthy of clinical note are currently unknown.
Contraindications CERULISINA ® Dimethylbenzene and sweet almond oil
The use of CERULISINE ® is contraindicated in patients with hypersensitivity to the drug or suffering from middle ear diseases.
Undesirable effects - Side effects
The use of CERULISINE ® is generally safe and well tolerated.
The onset of potential side effects, generally from sensitization, could occur more frequently following the inappropriate use of the drug.
Note
CERULISINE ® is a non-prescription drug.
