ALC Dymatize Nutrition

Information on ALC Dymatize Nutrition

Food supplement of acetyl L carnitine.

FORMAT

90 cps bottle

COMPOSITION

Acetyl L-Carnitine

Thiamine (vitamin B1)

Methionine

Capsule: edible gelatin and cellulose

Excipient: silicone dioxide.

Contains no cereals, yeasts, soy preservatives or artificial colorings.

Acetyl L-Carnitine 500 mg - known its role in transporting fatty acids from outside the mitochondrial membrane to the matrix, promoting oxidation; it is also part of the regulation of glucose metabolism, preventing the accumulation of acetyl-CoA in the mitochondrial side and normalizing the AcetylCoA / CoA ratio. The acetylated form of L-Carnitine also has a powerful antioxidant and neuroprotective action. Thanks to its mimetic colander action, and given its more lipophilic nature, intestinal absorption levels are also improved. Recent studies have shown the ability of acetyl L carnitine to preserve and enhance the oxidative capacity of muscle fibers (a study carried out on the rat soleus muscle), as well as the ALC has effectively proved useful in reducing the sensation of fatigue (study carried out on patients with multiple sclerosis).

Thiamine 25 mg - also known as vitamin B1, once introduced through the diet (very present in: whole grains, legumes, brewer's yeast) is absorbed in the intestine (duodenal) and distributed to various tissues. Here it undergoes a double process of phosphorylation, giving rise to TPP (thiamine pyrophosphate), which is part of the oxidative decarboxylation process, together with lipoic acid and a CoA supporting the functionality of pyruvate dehydrogenase, in the Krebs cycle, allowing the passage from α- ketoglutarate with Succinyl CoA, and in the pentose phosphate cycle. In addition, together with Vitamin B6 and Vitamin C in the presence of iron, it participates in the synthesis of carnitine, starting from lysine and methionine.

Its requirement is about 0.4 / 0.8 mg per 1000 kcal introduced.

Methionine 25mg - essential apolar amino acid, as it must necessarily be introduced with the diet (the richest foods are eggs, meats, fish and cheeses). It is part of the common protein synthesis, but is also important for the synthesis of biologically active molecules such as SAM (S adenosil methionine, an enzyme involved in trans-methylation reactions and hormone synthesis, and naturally in the synthesis of carnitine), choline and taurine ( involved in various biological functions: maintaining cellular osmolarity, safeguarding cellular membranes, bile salt synthesis, neurotransmission regulation, is probably able to increase the synthesis of nitric oxide and counteract oxidative stress).

Product features ALC Dymatize Nutrition

The product in question is an enriched acetyl L-carnitine supplement, compared to the basic supplements, with Thiamine and Methionine. Also the dosage (500mg) of the main compound (ALC) is strengthened compared to common supplements, for which concentrations are used around 200 mg per capsule. Instead, the chosen format remains unchanged: capsules for oral administration, able to bring the product unaltered to intestinal level, the site of its absorption.

The choice to associate the ALC with vitamin B1 and methionine could have a double advantage. On the one hand, thiamine could optimize glucidic and oxidative metabolism in general, effectively promoting the advancement of the citric acid cycle and eliminating acyl derivatives more quickly; on the other hand, methionine could enhance the antioxidant function of the product. Furthermore, vitamin B1 and methionine could increase the endogenous synthesis of carnitine, as long as they are accompanied by other cofactors and by the second essential amino acid lysine.

Recommended use by the company - ALC Dymatize Nutrition

1 - 2 cps a day in some water during meals.

Use in sports practice ALC Dymatize Nutrition

In sports practice the recruitment of ALC can follow different protocols. The most common ones foresee a gradual weekly ascent from 500 mg up to 2 / 2.5 g per day, others instead provide a descent from 2.5 g to 500 mg a day. Higher dosages in healthy subjects are not recommended, as the excess product would be excreted intact at renal level.

The optimization of supplementation with ALC should include aerobic exercises, able to maintain high pO2 in the muscular level, and possibly a reduction in the glucidic content of the diet.

Rationale for use - ALC Dymatize Nutrition

Supplementation with ALC for sporting purposes has not yet led to significant scientific studies, which describe a real advantage. However, there are numerous studies in the literature that demonstrate its numerous therapeutic potential in different diseases, demonstrating the effectiveness of this compound in reducing the sensation of fatigue, improving lipid metabolism, preserving neuronal function and protecting the brain from intense oxidative stress.

ALC Dymatize Nutrition side effects

At high doses episodes of insomnia, nausea, abdominal cramps, migraine and gastro intestinal disorders may occur, albeit rare.

Precautions for use ALC Dymatize Nutrition

Contraindicated in cases of renal, hepatic, diabetic, pregnancy, lactation, mood disorders.

This article, elaborated on the critical re-reading of scientific articles, university texts and common practice, is for informational purposes only and is therefore not a medical prescription. It is therefore always necessary to consult your doctor, nutritionist or pharmacist before starting to use any kind of supplement . Further information on the critical analysis of ALC Dymatize Nutrition.