FOILLE ® is a drug based on Benzyl Alcohol, Benzocaine and Chlorhexylenol
THERAPEUTIC GROUP: Emollients and protective agents
IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects
Indications FOILLE (Scalding) ® Alcohol Benzyl + Benzocaine + Clorixilenol
FOILLE ® is indicated for the treatment and dressing of skin lesions and skin irritation conditions such as irritation, burns, erythema and insect bites.
Mechanism of action FOILLE (Scalding) ® Alcohol Benzyl + Benzocaine + Clorixylenol
The therapeutic activity of FOILLE ® is associated with its active ingredients, with different and complementary biological properties, such as to extend the relative therapeutic indications to different morbid states.
More precisely :
- Benzocaine is an active ingredient with local anesthetic activity, blocking the depolarization of nociceptive and motor nerve fibers, thereby inhibiting pain transmission at the central level.
- Benzyl alcohol, on the other hand, is an aromatic organic compound, endowed with a marked antibacterial power against Gram positive bacteria, which gradually decreases against Gram negative yeast and fungus bacteria.
However, the bacteriostatic and partly bactericidal action preserves the damaged tissue from possible bacterial contamination.
- Clorixilenol is an antiseptic and disinfectant active against bacteria, algae and fungi which, by altering what is the normal structure of the bacterial membrane, thus compromises vital capacities.
The topical use of these products allows to check their toxicity, considerably limiting the side effects that would result from their systemic use.
Studies carried out and clinical efficacy
ANESTHETIC EFFECTIVENESS OF BENZOCAINE
Indian J Dent Res. 2006 Oct-Dec; 17 (4): 155-60.
A study that demonstrates how Benzocaine-based gels can have a faster and more effective analgesic activity, guaranteeing effective symptomatology control even in dental practice.
BENZOCAINE AND METAEMOGLOBINOPATHY
Am J Cardiovasc Drugs. 2013 May 22. [Epub ahead of print]
A study that denounces one of the potential side effects linked to the topical use of Benzocaine, such as methaemoglobinopathy, often the cause of serious disorders such as to cause a significant increase in morbidity and mortality.
Therefore, extreme caution is recommended when using Benzocaine-based medicines
CHLOROXYLOXOL IN UROPATOGENIC INFECTIONS
Clin Microbiol Infect. 2008 Feb; 14 (2): 190-2. Epub 2007 Nov 28.
Interesting work that evaluates the preventive efficacy of Chloroxylenol against infections sustained by uropathogenic germs, in patients subjected to catheterization. Such prevention would be important in controlling one of the most widespread infections in hospitals
Method of use and dosage
FOILLE ®
Cream for topical use with 4 g of Benzyl Alcohol, 5 g of Benzocaine and 0.10 g of Chloroxylenol per 100 g of product.
We recommend applying a thin and uniform layer of cream directly on the skin region to be treated, for a maximum of 4 daily applications.
Warnings FOILLE (Scalding) ® Alcohol Benzyl + Benzocaine + Clorixylenol
The correct use of FOILLE ® requires compliance with the following indications:
- Avoid contact with eyes and exposed mucous membranes;
- Avoid ingestion and inhalation of the product;
- Consult a doctor in the event of major and extensive injuries;
- Apply the cream for the shortest possible time;
- Contact your doctor immediately if the use of the cream causes the appearance of unpleasant side effects such as redness, swelling and irritation;
- Avoid using the drug in children under the age of 2 years.
PREGNANCY AND BREASTFEEDING
Despite the use of FOILLE ® there are no contraindications during pregnancy and the subsequent breastfeeding period, it would be appropriate to limit its use to cases of real need and always under strict medical supervision.
Interactions
It is recommended to avoid the simultaneous use of other antiseptics or detergents.
Contraindications FOILLE (Scalding) ® Alcohol Benzyl + Benzocaine + Clorixilenol
The use of FOILLE ® is contraindicated in patients who are hypersensitive to the active ingredient or to one of its excipients.
Undesirable effects - Side effects
The use of FOILLE ®, especially when continued for a long time, could determine the appearance of local side effects such as redness, burning and hives.
Note
FOILLE ® is a non-prescription drug.
