drugs

Drugs to treat renal colics

Definition

Renal colic is an acute and violent pain of the ureter, characterized by very strong contractions of the kidneys. In addition to renal ones, intestinal, hepato-biliary, pancreatic and gastric colics are remembered.

Causes

The very strong pain associated with renal colic depends on the passage of stones in the ureter, responsible for muscle spasm; however, colic may occur even in the absence of obstruction of urinary flow. The synthesis of prostaglandins, responsible for the pain, is favored by pressure violence, induced in turn by the obstruction of the urinary tract.

Symptoms

Renal colic can cause variable symptoms: abdominal and lumbar pain - often spread to the groin and genitals - hematuria (blood in the urine), fever, hypotension, intense sweating, nausea and vomiting.

Information on Renal Colics - Drugs for the Treatment of Renal Colic is not intended to replace the direct relationship between health professional and patient. Always consult your doctor and / or specialist before taking Renal Colic - Renal Colic Drugs.

drugs

It is necessary to underline that an isolated episode of renal colic must not alarm too much: in any case, it is good to consult the general practitioner, who will prescribe useful tests to ascertain the nature of colic. Recurrent renal colics, on the other hand, require specialist examination (urologist and nephrologist) and an appropriate pharmacological procedure.

The drugs are aimed at reducing the pain symptoms and eliminating the causes that generated the renal colic:

NSAID pain relief therapy: it is recommended not to delay and to take the anti-inflammatory drug starting from the onset of symptoms, after medical consultation.

  • Ketorolac trometamina (eg Toradol): used to relieve fever and pain associated with renal colic. The drug is in the form of tablets or vials: administer 10 mg of active ingredient orally or intravenously / intramuscularly, 3-4 times a day for a period less than or equal to 5 days. In case of severe pain, replace the drug with opioids.
  • Paracetamol or acetaminophen (eg Tachipirina, Buscopan compositum): in case of fever associated with renal colic, take the drug orally in the form of tablets, syrup, effervescent sachets or suppositories; it is recommended to take paracetamol at a dosage of 325-650 mg every 4-6 hours for 6-8 consecutive days, to bring down the fever.
  • Petidina (eg Petid C): for acute pain, take a dose equivalent to 50-150 mg every 4 hours, depending on the severity of the colic. For subcutaneous injection, administer 25-100 mg and repeat the application after 4 hours. For intramuscular injection, administer 0.5-2 mg of active ingredient per pound of body weight. Alternatively, for slow intravenous infusion, it is recommended to administer the drug at a dose of 25-50 mg (repeat after 4 hours).
  • Diclofenac (eg Fastum Painkiller, Dicloreum): preferable to pethidine. Take 50 mg of drug orally 3 times a day (tablets); in some patients, an initial dose of 100 mg is required, and then changed to 50 mg. After the first day, the total daily dose should not exceed 150 mg.

Antispasmodic drugs (to be combined with NSAIDs): they are useful for relaxing the muscles of the genito-urinary tract affected by colic. The administration of these drugs is useful for extracting the calculation responsible for renal colic.

  • The pharmaceutical specialty Antispasmina colica consists of belladonna and papaverine hydrochloride: these two active ingredients are indicated to reduce the pain symptoms of a spastic nature associated with renal colic (spasms caused by contractions of the smooth muscles of the gastrointestinal tract). Belladonna (anticholinergic therapeutic action) reduces the contraction of smooth muscles, guaranteeing a significant reduction in spastic pain. Take 2-6 sugared almonds - consisting of 10 mg of papaverine and 10 mg of belladonna - per day for the average pain caused by renal colic. In case of severity, take 1-3 tablets of 50 mg of papaverine and 10 mg of belladonna per day.

Antiemetics : in the case of renal colic associated with nausea / vomiting, the administration of antinausea / antiemetic drugs is recommended. For example, the administration of Scopolamine butyl bromide (eg Addofix) is recommended, particularly useful for giving relief to spastic pain in the genitourinary and gastrointestinal tract.

Antibiotics : when colic is caused by bacterial infections, the doctor prescribes antibiotics to the patient in order to remove the pathogens responsible for the infection.

Rest and improvement of the patient's diet and lifestyle are useful for completing therapeutic measures in the presence of renal colic.