Category blood health

Generality Myelofibrosis is a bone marrow disease. Particularly striking is haemopoietic stem cells, used for the production of red blood cells, white blood cells and platelets. The alteration of the haematopoietic function of the bone marrow results in a decline of mature cells in the blood, especially red blood cells; this determines the typical signs of the disease, among which the main ones are anemia and splenomegaly (enlargement of the spleen); numerous other symptoms and, sometimes, serious complications can also arise

Generality Myelosuppression is a medical condition characterized by reduced production of blood cells by the bone marrow. Also known as myelodepression or myelotoxicity, it is one of the most important side effects of chemotherapy treatments used to treat cancer. Not all of these drugs induce myelodepression and its extent depends - in addition to the type of drug - on the doses, on the methods of administration, on the patient's health and on the number of administrations previously performed

Generality Acute leukemia tends to become severe rapidly and, therefore, must be treated as soon as possible. If left untreated, the disease is lethal. The therapeutic objective is to obtain the regression of leukemic cells (remission) and a normalization of blood values. Reaching these conditions is not always possible

Generality Bone marrow transplantation , also called hematopoietic stem cell transplantation , is the therapeutic treatment with which a sick bone marrow is replaced with another healthy one, in order to restore normal blood cell production. The procedure is very complex and, in order for it to be carried out, it requires different conditions: among all of them, a good patient's state of health (in spite of the illness that afflicts him) and the impracticability of any other alternative intervention

Generality Thrombolysis is the pharmacological treatment that allows dissolving a thrombus or an embolus, present in an artery or in a vein. Implemented by specialized medical figures, thrombolysis involves the administration of particular drugs, called fibrinolytics (or thrombolytics), and an X-ray instrumentation to observe the outcome

Definition Fanconi anemia is a hereditary form of aplastic anemia, that is, a clinical syndrome that is expressed with a picture of global hypoaplasia of the three major proliferative marrow supply chains (from which result white blood cells, erythrocytes and platelets). This results in peripheral pancytopenia (deficiency of all types of blood cells)

Related articles: Anemia Definition Anemia is a condition in which the number of red blood cells in the blood falls below the norm. The symptoms of anemia are mainly due to the reduced availability of oxygen in the tissues, since red blood cells are essential for the transport of this gas in the circulatory stream

Definition Autoimmune hemolytic anemia is a blood disorder characterized by the presence of abnormal antibodies directed against red blood cells; these immune cells bind to the red blood cell membrane, reducing their survival and causing their premature destruction by hemolysis. This form of hemolytic anemia of immune origin recognizes various causes

Related articles: Hemolytic Anemia Definition Hemolytic anemias are a group of haematological diseases characterized by a shortening of the average life of red blood cells in the circulation (this usually coincides about 120 days) and their premature destruction by extra-and / or intravascular hemolysis

Definition Disseminated intravascular coagulation (CID) is a syndrome characterized by an abnormal activation of the blood coagulation process, capable of causing an uncontrolled generation of thrombin and fibrin in the circulating blood. This condition is secondary to various disease states, including sepsis, obstetric complications (such as abruptio placentae, retention of products of conception and embolism of amniotic fluid), haematological malignancies (including acute leukemias and lymphomas), liver diseases (eg fulminant hepatitis ) and extensive tissue damage (burns, hyperthermia, crush