TRIENE ® Polyenacidin

TRIENE ® is a polyenacidin based drug.

THERAPEUTIC GROUP: Emollients and protective agents

IndicationsAction mechanismStudies and clinical effectiveness Usage and dosage instructionsWarnings Pregnancy and lactationInteractionsContraindicationsUndesirable effects

Indications TRIENE ® Polyenacidin

TRIENE ® is indicated for the protection and treatment of dermatological lesions induced by chemical, physical and atmospheric agents.

Mechanism of action TRIENE ® Polyenacidin

TRIENE ® is a drug based on Polyenacidin, a mixture of polyunsaturated fatty acids such as linolenic and linoleic acid, which, applied to the skin region to be treated, is able to form a thin protective lipid film capable of protecting the skin while preserving levels hydration of the same.

Molecular studies have also characterized the biological activity of polyunsaturated fatty acids used topically, demonstrating their ability to promote skin regeneration by inducing re-epithelialization through the induction of the biological cycle.

The same lipid film protects the skin from any fluid loss, often associated with dehydration and longer healing times.

Studies carried out and clinical efficacy

THE LINOLEIC ACID IN THE TREATMENT OF ACNE

Int J Cosmet Sci. 2011 Oct; 33 (5): 467-76. doi: 10.1111 / j.1468-2494.2011.00658.x. Epub 2011 Jun 13.

Topical clindamycin 1% vs. linoleic acid-rich phosphatidylcholine and nicotinamide 4% in the treatment of acne: a multicentre-randomized trial.

Morganti P, Berardesca E, Guarneri B, Guarneri F, Fabrizi G, Palombo P, Palombo M.

Interesting work that demonstrates the effectiveness of linoleic acid used topically in normalizing the skin lesions present during acne, reducing the inflammatory extent of the same and controlling hyperkeratinization.

POLYSATURED FATTY ACIDS BY ROUTE AND VENOUS ULCERS

Rev Enferm. 2008 Apr; 3: 219-25. doi: 10.1001 / archophthalmol.2007.61.

Innovative study that evaluates the possibility of using polyunsaturated fatty acids in ophthalmological solution for the treatment of some eye pathologies. This treatment proved to be effective in reducing the main markers and signs of inflammation.

Method of use and dosage

TRIENE ®

Topical cream with 5 g of Polyenacidin per 100 g of product.

It is generally recommended to apply the correct amount of cream on the region to be treated twice a day, taking care to gently massage the region itself in case of erythema or to slightly compress with sterile gauze in case of deep lesions.

Warnings TRIENE ® Polyenacidin

Given the topical use of TRIENE ® it is advisable to exercise extreme caution in its use, avoiding ingestion or contact with mucous membranes.

The use of TRIENE ®, especially if continued for a long time, could determine the appearance of adverse hypersensitivity reactions such as irritation and burning.

In this case it would be advisable to immediately stop taking the product by consulting your doctor and taking into consideration the possibility of suspending the therapy in progress.

It is recommended to store the product in a cool and dry place, out of reach of children.

PREGNANCY AND BREASTFEEDING

Although there are no absolute contraindications regarding the use of TRIENE ® during pregnancy and in the subsequent breastfeeding period, it would be useful to use this medicine exclusively in cases of real need and under strict medical supervision.